Efficient Genome Editing of Immune Cells Using Microfluidic Delivery as a Novel Approach to Cell Therapy

被引：0
|
作者：
Hanson, Jacquelyn L. S. [1 ]
Cole, Julie M. [1 ]
Cassereau, Luke [1 ]
Bugge, Joshua A. [1 ]
DiTommaso, Tia [1 ]
Gilbert, Jonathan [1 ]
Beutel, Bruce A. [1 ]
Bernstein, Howard [1 ]
Sharei, Armon [1 ]
机构：
[1] SQZ Biotechnol, Watertown, MA USA
来源：
MOLECULAR THERAPY | 2018年 / 26卷 / 05期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
158
引用
收藏
页码：75 / 75
页数：1
相关论文
共 50 条
  • [1] Microfluidic Droplet Cell Mechanoporation Enables Highly Efficient Genome Editing in Human Primary Immune Cells
    Joo, Byeongju
    Kim, You-Jeong
    Yun, Da Young
    Jung, Cheulhee
    Chung, Aram
    MOLECULAR THERAPY, 2023, 31 (04) : 732 - 733
  • [2] Highly Efficient Genome Editing of Human Primary Immune Cells Using Scalable Microfluidic Droplet-Enabled Cell Mechanoporator
    Joo, Byeongju
    Kim, You-Jeong
    Yun, Dayoung
    Im, Sungbin
    Jung, Cheulhee
    Chung, Aram
    MOLECULAR THERAPY, 2024, 32 (04) : 370 - 370
  • [3] Vector Free Genome Editing of Immune Cells for Cell Therapy
    DiTommaso, Tia
    Gilbert, Jonathan
    Bernstein, Howard
    Sharei, Armon
    MOLECULAR THERAPY, 2016, 24 : S229 - S229
  • [4] Vector-free genome editing of immune cells for cell therapy
    Cassereau, Luke
    DiTommaso, Tia
    Loughhead, Scott
    Gilbert, Jonathan
    Bernstein, Howard
    Sharei, Armon
    CANCER IMMUNOLOGY RESEARCH, 2018, 6 (09)
  • [5] Vector-Free Genome Editing of Primary Immune Cells for Cell Therapy
    Bridgen, Devin
    DiTommaso, Tia
    Bugge, Joshua
    Gilbert, Jonathan
    Bernstein, Howard
    Sharei, Armon
    MOLECULAR THERAPY, 2017, 25 (05) : 23 - 24
  • [6] Novel Microfluidic Delivery Device for CRISPR Cas9 Editing of T Cells for Adoptive Cellular Therapy
    Yu, Tong
    Jhita, Navdeep
    Shankles, Peter G.
    Raikar, Sunil S.
    Sulchek, Todd A.
    MOLECULAR THERAPY, 2022, 30 (04) : 448 - 448
  • [7] Efficient delivery of nuclease proteins for genome editing in human stem cells and primary cells
    Liu, Jia
    Gaj, Thomas
    Yang, Yifeng
    Wang, Nan
    Shui, Sailan
    Kim, Sojung
    Kanchiswamy, Chidananda Nagamangala
    Kim, Jin-Soo
    Barbas, Carlos F., III
    NATURE PROTOCOLS, 2015, 10 (11) : 1842 - 1859
  • [8] Efficient delivery of nuclease proteins for genome editing in human stem cells and primary cells
    Jia Liu
    Thomas Gaj
    Yifeng Yang
    Nan Wang
    Sailan Shui
    Sojung Kim
    Chidananda Nagamangala Kanchiswamy
    Jin-Soo Kim
    Carlos F Barbas
    Nature Protocols, 2015, 10 : 1842 - 1859
  • [9] Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles
    Wang, Ming
    Zuris, John A.
    Meng, Fantao
    Rees, Holly
    Sun, Shuo
    Deng, Pu
    Han, Yong
    Gao, Xue
    Pouli, Dimitra
    Wu, Qi
    Georgakoudi, Irene
    Liu, David R.
    Xu, Qiaobing
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 113 (11) : 2868 - 2873
  • [10] Highly efficient CRISPR-mediated genome editing through microfluidic droplet cell mechanoporation
    Kim, You-Jeong
    Yun, Dayoung
    Lee, Jungjoon K.
    Jung, Cheulhee
    Chung, Aram J.
    NATURE COMMUNICATIONS, 2024, 15 (01)
12345