The product bears the shock load during the circulation process. 'e cushioning materials need to absorb the energy generated during the shock to prevent damage to the product. 'e cushion packaging system generally consists of products, cushioning materials, and an outside packaging carton. 'erefore, it is necessary to study the factors affecting the cushion performance of the system. 'is paper adopts a BP neural network to develop a more precise constitutive relationship. Based on the trained constitutive network model, the dynamic equation of the system is established, and the Runge-Kutta algorithm is utilized to resolve it. 'e multiobjective optimization (MOP) model of the series cushioning system is established for the first time. 'e model considers more factors, such as the stability of the cushioning material and whether to use local cushioning. 'e factors affecting the performance of the cushioning system are deeply studied, and a variety of evolutionary algorithms (PESA2, SPEA2, MOPSO, MOEA/D, and NSGAII) are utilized to solve the multi-objective optimization problem. 'e performances of the solution sets obtained by the evolutionary algorithms are studied based on several performance indicators. 'e results show that these solution sets have good convergence, and the all-around performance of NSGA-II ranks first. Finally, comparing the knee point of the non-dominated solution set calculated by NSGA-II with the parameters in the literature, it is found that the former has better defense performance and less material consumption, which can be used for future product design. 'erefore, the evolutionary algorithm can favorably resolve the multiobjective optimization of the series cushioning packaging system under the dropping shock.