Neoadjuvant Use of Ipilimumab in Locally Advanced Melanoma

被引：7

作者：

Howie, Lynn J. ^{[1
,2
]}

Tyler, Douglas S. ^{[2
]}

Salama, April K. S. ^{[1
,3
]}

机构：

[1] Duke Univ, Div Med Oncol, Trinity, NC USA

[2] Univ Texas Med Branch, Dept Surg, Galveston, TX 77555 USA

[3] Duke Canc Inst, Durham, NC USA

来源：

JOURNAL OF SURGICAL ONCOLOGY | 2015年 / 112卷 / 08期

关键词：

melanoma; ipilimumab; immunotherapy; neoadjuvant; RESECTION; PATIENT; TRIAL;

D O I：

10.1002/jso.24079

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Recent advances in immune modulating therapies show great promise for patients with advanced melanoma, however optimal strategies for achieving long-term disease control in locally advanced melanoma are unclear. We present two cases of neoadjuvant ipilimumab, one case in combination with isolated limb infusion (ILI) followed by surgical resection and one followed by surgery alone. Both patients have had durable responses. These cases highlight the ongoing need for prospective trials in the neoadjuvant setting. (C) 2015 Wiley Periodicals, Inc.

引用

页码：841 / 843

页数：3

共 50 条

[1] Neoadjuvant Ipilimumab/Nivolumab combination in locally advanced or oligometastatic melanoma
Ferrucci, Pier Francesco
Lanfrancone, Luisa
Mazzarella, Luca
Nezi, Luigi
Duso, Bruno Achutti
Manzo, Teresa
Lotti, Fiorenza
Gandini, Sara
Orsolini, Gianmarco
Pennacchioli, Elisabetta
Gnagnarella, Patrizia
Fierro, Maria Teresa
Senetta, Rebecca
Riviello, Concetta
Caliendo, Virginia
Quaglino, Pietro
Mazzarol, Giovanni
Bonizzi, Giuseppina
Cocorocchio, Emilia
[J]. JOURNAL OF TRANSLATIONAL MEDICINE, 2022, 20 (SUPPL 1)
[2] Neoadjuvant ipilimumab in locally/regionally advanced melanoma: Clinical outcome and biomarker analysis
Tarhini, Ahmad A.
Edington, Howard
Butterfield, Lisa H.
Shuai, Yongli
Lin, Yan
Rao, Uma N.
Kirkwood, John M.
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (30)
[3] Neoadjuvant ipilimumab in locally/regionally advanced melanoma: Clinical outcome and immune monitoring
Tarhini, Ahmad A.
Edington, Howard
Butterfield, Lisa H.
Tawbi, Hussein
Moschos, Stergios J.
Shuai, Yongli
Lin, Yan
Horak, Mary
Sarkisian, Saro
Shipe-Spotloe, Janice
Milburn, Christy
Sander, Cindy
Johnson, Jonas Talmadge
Kirkwood, John M.
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)
[4] Neoadjuvant Immunotherapy for Locally Advanced Melanoma
Meredith S. Pelster
Rodabe N. Amaria
[J]. Current Treatment Options in Oncology, 2020, 21
[5] Neoadjuvant Immunotherapy for Locally Advanced Melanoma
Pelster, Meredith S.
Amaria, Rodabe N.
[J]. CURRENT TREATMENT OPTIONS IN ONCOLOGY, 2020, 21 (02)
[6] Preliminary results of a Neoadjuvant combo-immunotherapy with ipilimumab and nivolumab in locally advanced or limited metastatic melanoma
Ferrucci, Pier Francesco
Pala, Laura
Conforti, Fabio
Nezi, Luigi
Manzo, Teresa
Cocorocchio, Emilia
[J]. JOURNAL OF TRANSLATIONAL MEDICINE, 2020, 18
[7] Neoadjuvant therapy of locally/regionally advanced melanoma
Khunger, Arjun
Buchwald, Zachary S.
Lowe, Michael
Khan, Mohammad K.
Delman, Keith A.
Tarhini, Ahmad A.
[J]. THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY, 2019, 11
[8] Ipilimumab: A Guide to Its Use in Advanced Melanoma
Lyseng-Williamson, Katherine A.
Sanford, Mark
[J]. AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 2012, 13 (05) : 349 - 354
[9] Ipilimumab: A Guide to Its Use in Advanced Melanoma
Katherine A. Lyseng-Williamson
Mark Sanford
[J]. American Journal of Clinical Dermatology, 2012, 13 : 349 - 354
[10] Challenges and Opportunities of Neoadjuvant Treatment in Locally Advanced Melanoma
Meredith A. McKean
Rodabe N. Amaria
[J]. American Journal of Clinical Dermatology, 2018, 19 : 639 - 646

← 1 2 3 4 5 →