Polymeric IgA from patients with IgA nephropathy (IgAN) downregulates the angiotensin II receptor type 1 (AT1R) gene expression in human mesangial cells (HMC).

被引:0
|
作者
Lai, KN [1 ]
Tang, SCW [1 ]
Tsang, AWL [1 ]
Chan, LYY [1 ]
Leung, JCK [1 ]
机构
[1] Univ Hong Kong, Hong Kong, Hong Kong, Peoples R China
关键词
D O I
暂无
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:664A / 665A
页数:2
相关论文
共 50 条
  • [1] Mesangial expression of angiotensin II receptor in IgA nephropathy and its regulation by polymeric IgA1
    Lai, KN
    Chan, LYY
    Tang, SCW
    Tsang, AWL
    Li, FFK
    Lam, MF
    Lui, SL
    Leung, JCK
    KIDNEY INTERNATIONAL, 2004, 66 (04) : 1403 - 1416
  • [2] Charge-dependent binding of polymeric IgA1 to human mesangial cells in IgA nephropathy
    Leung, JCK
    Tang, SCW
    Lam, MF
    Chan, TM
    Lai, KN
    KIDNEY INTERNATIONAL, 2001, 59 (01) : 277 - 285
  • [3] Integrin α1/β1 and α2/β1 as a receptor for IgA1 in human glomerular mesangial cells in IgA nephropathy
    Kaneko, Yoshikatsu
    Otsuka, Tadashi
    Tsuchida, Yohei
    Gejyo, Fumitake
    Narita, Ichiei
    INTERNATIONAL IMMUNOLOGY, 2012, 24 (04) : 219 - 232
  • [4] Transferrin receptor engagement by polymeric IgA1 induces receptor expression and mesangial cell proliferation: Role in IgA nephropathy
    Tamouza, Honda
    Vende, Florence
    Tiwari, Meetu
    Arcos-Fajardo, Michelle
    Vrtovsnik, Francois
    Benhamou, Marc
    Monteiro, Renato C.
    Moura, Ivan C.
    IGA NEPHROPATHY TODAY, 2007, 157 : 144 - 147
  • [5] Expression of angiotensin II type 1 receptor-interacting molecule in normal human kidney and IgA nephropathy
    Masuda, Shin-ichiro
    Tamura, Kouichi
    Wakui, Hiromichi
    Maeda, Akinobu
    Dejima, Toru
    Hirose, Tomonori
    Toyoda, Masao
    Azuma, Koichi
    Ohsawa, Masato
    Kanaoka, Tomohiko
    Yanagi, Mai
    Yoshida, Shin-ichiro
    Mitsuhashi, Hiroshi
    Matsuda, Miyuki
    Ishigami, Tomoaki
    Toya, Yoshiyuki
    Suzuki, Daisuke
    Nagashima, Yoji
    Umemura, Satoshi
    AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2010, 299 (04) : F720 - F731
  • [6] Increased binding of polymeric lambda-IgA isolated from patients with IgA ephropathy (IgAN) by cultured human mesangial cells.
    Lai, KN
    To, WY
    Leung, JCK
    KIDNEY INTERNATIONAL, 1997, 51 (04) : 1319 - 1320
  • [7] IgA1 immune complexes from pediatric patients with IgA nephropathy activate cultured human mesangial cells
    Novak, Jan
    Kafkova, Leona Raskova
    Suzuki, Hitoshi
    Tomana, Milan
    Matousovic, Karel
    Brown, Rhubell
    Hall, Stacy
    Sanders, John T.
    Eison, T. Matthew
    Moldoveanu, Zina
    Novak, Lea
    Novak, Zdenek
    Mayne, Richard
    Julian, Bruce A.
    Mestecky, Jiri
    Wyatt, Robert J.
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 2011, 26 (11) : 3451 - 3457
  • [8] Binding capacity and pathophysiological effects of IgA1 from patients with IgA nephropathy on human glomerular mesangial cells
    Wang, Y
    Zhao, MH
    Zhang, YK
    Li, XM
    Wang, HY
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2004, 136 (01): : 168 - 175
  • [9] Polymeric IgA1 from patients with IgA nephropathy upregulates transforming growth factor-β synthesis and signal transduction in human mesangial cells via the renin-angiotensin system
    Lai, KN
    Tang, SCW
    Guh, JY
    Chuang, TD
    Lam, MF
    Chan, LYY
    Tsang, AWL
    Leung, JCK
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2003, 14 (12): : 3127 - 3137
  • [10] EXPRESSION OF CD71 MESANGIAL IGA1 RECEPTOR PREDICTS PROGRESSION OF IGA NEPHROPATHY
    Yun, Hae-Ryong
    Jhee, Jong Hyun
    Kang, Shin-Wook
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 2018, 33