Synthesis of deuterium-labeled cyamemazine and monodesmethyl cyamemazine

被引：0
|
作者：
Bolla, R. Sekhar [1 ]
Kasi Viswanath, I. V. [1 ]
机构：
[1] KL Univ, Dept Chem, Vaddeswaram, India
来源：
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS | 2014年 / 57卷 / 02期
关键词：
schizophrenia; H-2(6)]cyamemazine maleate; N-desmethyl-[H-2(3)]cyamemazine maleate; antipsychotic; cyamepromazine; deuterium labeled; DRUG;
D O I：
10.1002/jlcr.3145
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A novel approach is presented for the synthesis of cyamemazine maleate and N-desmethyl cyamemazine maleate using a 10-(amino-2-methylpropyl)phenothiazine derivative. This method was successfully applied to the synthesis of [H-2(6)]cyamemazine maleate and N-desmethyl-[H-2(3)]cyamemazine maleate. Copyright (c) 2013 John Wiley & Sons, Ltd.
引用
收藏
页码：82 / 85
页数：4
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