COLORECTAL CANCER Irinotecan therapy-following a trail of breadcrumbs?

被引：1
|
作者：
Goldberg, Richard M. [1 ]
O'Neil, Bert H. [1 ]
机构：
[1] Univ N Carolina, Div Hematol & Oncol, Chapel Hill, NC 27599 USA
来源：
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY | 2009年 / 6卷 / 09期
关键词：
CHEMOTHERAPY; TRIAL; BEVACIZUMAB; CETUXIMAB; FAILURE;
D O I：
10.1038/nrgastro.2009.140
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
The optimal therapy for patients with metastatic and treatment-refractory colorectal cancer is controversial. Questions with regard to both the sequence and combinations of different drugs need to be answered by well-designed and adequately powered studies before the most appropriate option for second-line treatment for these patients can be defined.
引用
收藏
页码：507 / 509
页数：4
相关论文
共 50 条
  • [1] Irinotecan therapy—following a trail of breadcrumbs?
    Richard M. Goldberg
    Bert H. O'Neil
    [J]. Nature Reviews Gastroenterology & Hepatology, 2009, 6 : 507 - 509
  • [2] ?TRAIL? of targeted colorectal cancer therapy
    Jain, Nishakumari
    Roychowdhury, Parikshit
    Bhuyan, Nihar Ranjan
    Kuppusamy, Gowthamarajan
    [J]. INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS, 2023, 60 (02): : 95 - 98
  • [3] Following the protein biomarker trail to colorectal cancer
    Coghlin, Caroline
    Murray, Graeme I.
    [J]. COLORECTAL CANCER, 2012, 1 (02) : 93 - 96
  • [4] Therapy with cetuximab and irinotecan in refractory metastatic colorectal cancer
    [J]. Nature Clinical Practice Oncology, 2008, 5 (9): : 497 - 498
  • [5] Irinotecan therapy and molecular targets in colorectal cancer: A systemic review
    Jessica Weekes
    Alfred King-Yin Lam
    Sabe Sebesan
    Yik-Hong Ho
    [J]. World Journal of Gastroenterology, 2009, 15 (29) : 3597 - 3602
  • [6] Irinotecan therapy and molecular targets in colorectal cancer: A systemic review
    Weekes, Jessica
    Lam, Alfred King-Yin
    Sebesan, Sabe
    Ho, Yik-Hong
    [J]. WORLD JOURNAL OF GASTROENTEROLOGY, 2009, 15 (29) : 3597 - 3602
  • [7] Sensitization of colorectal cancer to irinotecan therapy by PARP inhibitor rucaparib
    Augustine, Titto
    Maitra, Radhashree
    Zhang, Jinghang
    Nayak, Jay
    Goel, Sanjay
    [J]. INVESTIGATIONAL NEW DRUGS, 2019, 37 (05) : 948 - 960
  • [8] Sensitization of colorectal cancer to irinotecan therapy by PARP inhibitor rucaparib
    Titto Augustine
    Radhashree Maitra
    Jinghang Zhang
    Jay Nayak
    Sanjay Goel
    [J]. Investigational New Drugs, 2019, 37 : 948 - 960
  • [9] Irinotecan in second-line therapy of metastatic colorectal cancer
    Jäger, E
    Jäger, D
    Orth, J
    Knuth, A
    [J]. ONKOLOGIE, 2000, 23 : S15 - S17
  • [10] Irinotecan in the treatment of colorectal cancer
    Fuchs, Charles
    Mitchell, Edith P.
    Hoff, Paulo M.
    [J]. CANCER TREATMENT REVIEWS, 2006, 32 (07) : 491 - 503
12345