Massive citalopram overdose associated with recurrent seizures and bilateral shoulder dislocations

被引:0
|
作者
Zoofaghari, Shafeajafar [1 ]
Wong, Anselm [2 ,3 ,4 ]
Kiarasi, Pegah [5 ]
Gheshlaghi, Farzad [1 ]
机构
[1] Isfahan Univ Med Sci, Sch Med, Dept Clin Toxicol, Isfahan Clin Toxicol Res Ctr, Esfahan, Iran
[2] Austin Hlth, Emergency Dept, Victorian Poisons Informat Ctr, Austin Toxicol Unit, Heidelberg, Vic, Australia
[3] Monash Univ, Sch Clin Sci Monash Hlth, Dept Med, Melbourne, Vic, Australia
[4] Univ Melbourne, Melbourne Med Sch, Dept Med & Radiol, Ctr Integrated Crit Care, Melbourne, Vic, Australia
[5] Isfahan Univ Med Sci, Sch Med, Dept Clin Toxicol, Esfahan, Iran
关键词
Citalopram; seizure; shoulder dislocation; TOXICITY;
D O I
10.4103/jrpp.JRPP_20_24
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Selective serotonin reuptake inhibitors (SSRIs) are widely used in the treatment of many types of mental disorders. Citalopram is commonly used as a new generation of SSRIs in this regard; however, unfortunately, its overdose is associated with seizure and heart disorders. The reported case in the present study indicated recurrent seizures, nonspecific ST-T changes, and prolonged QT interval due to the overuse of citalopram. The patient had bilateral anterior shoulder dislocation along with right proximal humerus fracture that was occurred during the seizure. The dislocation was initially reduced and then fixed. Moreover, the seizure was controlled with diazepam without any problems, and cardiac monitoring continued for 2 days. Massive citalopram overdose may be associated with recurrent seizures and QT prolongation. Complications postseizures, such as shoulder dislocations, should be examined for and managed appropriately.
引用
收藏
页码:161 / 164
页数:4
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