Efficient Methodology for the Synthesis of 3-Amino-1,2,4-triazoles

被引：21

作者：

Noel, Romain

Song, Xinyi

Jiang, Rong

Chalmers, Michael J.

Griffin, Patrick R.

Kamenecka, Theodore M. ^{[1
]}

机构：

[1] Scripps Florida, Scripps Res Inst, Dept Mol Therapeut, Jupiter, FL 33458 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2009年 / 74卷 / 19期

基金：

美国国家卫生研究院;

关键词：

NITROGEN-CONTAINING HETEROCYCLES; 1,2,4-TRIAZOLE DERIVATIVES;

D O I：

10.1021/jo9016502

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A general and efficient method for the preparation of 3-amino-1,2,4-triazoles has been developed. The desired 3-amino-1,2,4-triazoles (1) were prepared in good overall yield via two convergent routes. The key intermediate within both routes is substituted hydrazinecarboximidamide derivative 2.

引用

页码：7595 / 7597

页数：3

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