A role for the cerebellum in motor speech planning:: Evidence from foreign accent syndrome

被引:49
|
作者
Marien, Peter
Verhoeven, Jo
Engelborghs, Sebastiaan
Rooker, Servan
Pickut, Barbara A.
De Deyn, Peter P.
机构
[1] Middelheim Hosp, Dept Neurol & Memory Clin, B-2020 Antwerp, Belgium
[2] Univ Antwerp, Inst Born Bunge, Lab Neurochem & Behav, Antwerp, Belgium
[3] Free Univ Brussels, Dept Linguist, Brussels, Belgium
[4] Univ Antwerp, Dept Linguist, Antwerp, Belgium
关键词
cerebellum; foreign accent syndrome; apraxia of speech; SPECT;
D O I
10.1016/j.clineuro.2005.06.006
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
A 3 year follow-up study was performed in a patient with foreign accent syndrome (FAS) as the sole cognitive manifestation of a left fronto-parietal stroke. The hypothesis of involvement of the right cerebellum in this motor speech planning disorder was investigated by means of functional neuroimaging (SPECT) and neurobehavioral assessments. Based on the close parallelism between the evolution of FAS symptoms and the perfusional changes in the right cerebellum, it is argued that FAS may result from a disruption of a close functional interplay between the supra- and infratentorial speech centers involved in motor speech planning. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码:518 / 522
页数:5
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