A method to quantify the uptake rate of 2-[18F]fluoro-2-deoxy-D-glucose in tissues
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作者:
Laffon, E
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Ctr Hosp Univ Bordeaux, Nucl Med Serv, Hop Haut Leveque, F-33604 Pessac, FranceCtr Hosp Univ Bordeaux, Nucl Med Serv, Hop Haut Leveque, F-33604 Pessac, France
Laffon, E
[1
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Allard, M
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机构:Ctr Hosp Univ Bordeaux, Nucl Med Serv, Hop Haut Leveque, F-33604 Pessac, France
Allard, M
Marthan, R
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机构:Ctr Hosp Univ Bordeaux, Nucl Med Serv, Hop Haut Leveque, F-33604 Pessac, France
Marthan, R
Ducassou, D
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机构:Ctr Hosp Univ Bordeaux, Nucl Med Serv, Hop Haut Leveque, F-33604 Pessac, France
Ducassou, D
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[1] Ctr Hosp Univ Bordeaux, Nucl Med Serv, Hop Haut Leveque, F-33604 Pessac, France
[2] Univ Victor Segalen Bordeaux 2, Lab Physiol Cellulaire Resp, INSERM, EMI 0356, Bordeaux, France
A two-compartment model is used to derive the tissue time-activity curve of 2-[F-18]fluoro-2-deoxy-D-glucose (F-18-FDG). At the later phase of the F-18-FDG activity in the tissue, the model leads to a method which allows the assessment of the F-18-FDG uptake rate constant. The proposed method is both compared with the standard uptake value (SUV) method and with Patlak's graphical analysis. (C) 2004 Lippincott Williams Wilkins.
机构:
Laboratory of Radiochemistry, Department of Chemistry, University of Helsinki, Helsinki, FinlandLaboratory of Radiochemistry, Department of Chemistry, University of Helsinki, Helsinki, Finland
Kyllonen, T.
Küamüarüainen, E.L.
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Laboratory of Radiochemistry, Department of Chemistry, University of Helsinki, Helsinki, FinlandLaboratory of Radiochemistry, Department of Chemistry, University of Helsinki, Helsinki, Finland