A method to quantify the uptake rate of 2-[18F]fluoro-2-deoxy-D-glucose in tissues

被引:10
|
作者
Laffon, E [1 ]
Allard, M
Marthan, R
Ducassou, D
机构
[1] Ctr Hosp Univ Bordeaux, Nucl Med Serv, Hop Haut Leveque, F-33604 Pessac, France
[2] Univ Victor Segalen Bordeaux 2, Lab Physiol Cellulaire Resp, INSERM, EMI 0356, Bordeaux, France
关键词
PET; F-18-FDG; kinetic modelling; SUV; Patlak's slope;
D O I
10.1097/01.mnm.0000136729.42108.1a
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
A two-compartment model is used to derive the tissue time-activity curve of 2-[F-18]fluoro-2-deoxy-D-glucose (F-18-FDG). At the later phase of the F-18-FDG activity in the tissue, the model leads to a method which allows the assessment of the F-18-FDG uptake rate constant. The proposed method is both compared with the standard uptake value (SUV) method and with Patlak's graphical analysis. (C) 2004 Lippincott Williams Wilkins.
引用
收藏
页码:851 / 854
页数:4
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