Exercise, Inflammation, and Innate Immunity

被引:120
|
作者
Woods, Jeffrey A. [1 ,2 ,3 ]
Vieira, Victoria J. [1 ,3 ]
Keylock, K. Todd [1 ]
机构
[1] Univ Illinois, Dept Kinesiol & Community Hlth, Urbana, IL 61801 USA
[2] Univ Illinois, Dept Pathol, Urbana, IL USA
[3] Univ Illinois, Div Nutr Sci, Urbana, IL USA
关键词
Innate immunity; Exercise; Macrophages; C-REACTIVE PROTEIN; NECROSIS-FACTOR-ALPHA; PHYSICAL-ACTIVITY; WEIGHT-LOSS; ADIPOSE-TISSUE; INSULIN SENSITIVITY; CARDIOVASCULAR-DISEASE; OXIDATIVE STRESS; SKELETAL-MUSCLE; PLASMA-LEVELS;
D O I
10.1016/j.iac.2009.02.011
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Exercise has beneficial effects on chronic disease, and the drive to understand the mechanisms of these benefits is strong. This article presents several compelling potential mechanisms for the anti-inflammatory effect of exercise, including reduced percentage of body fat and macrophage accumulation in adipose tissue, muscle-released interleukin-6 inhibition of tumor necrosis factor-a, and the cholinergic anti-inflammatory pathway.
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页码:381 / +
页数:14
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