Comptexity in the immune system: New opportunities for chemical, engineering research

被引：4
|
作者：
Deem, MW [1 ]
机构：
[1] Rice Univ, Houston, TX 77005 USA
来源：
AICHE JOURNAL | 2004年 / 50卷 / 04期
关键词：
immune system; statistical mechanics; original antigenic sin;
D O I：
10.1002/aic.10068
中图分类号：
TQ [化学工业];
学科分类号：
0817 ;
摘要：
One may imagine that an analysis of the immune system would be immune from chemical engineering analysis. This Perspective shows how methods from statistical mechanics and computer simulation can be used to construct quantitative models of limitations in the immune system. Applications to dengue fever, which strikes 100 million people each year and is one of the most important human viral diseases, and cancer are given. Our challenge is to translate the understanding that these models provide into strategies, treatments, and the large-scale commercial production of vaccines and therapeutics.
引用
收藏
页码：734 / 738
页数：5
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