Mapping the new molecular landscape: social dimensions of epigenetics

被引:65
|
作者
Pickersgill, Martyn [1 ]
Niewoehner, Joerg [2 ]
Mueller, Ruth [3 ]
Martin, Paul [4 ]
Cunningham-Burley, Sarah [1 ]
机构
[1] Univ Edinburgh, Ctr Populat Hlth Sci, Old Med Sch, Edinburgh EH8 9AG, Midlothian, Scotland
[2] Humboldt Univ, D-10099 Berlin, Germany
[3] Lund Univ, Lund, Sweden
[4] Univ Sheffield, Sheffield, S Yorkshire, England
基金
英国惠康基金;
关键词
epigenetics; promise; novelty; social science; cancer; methylation; DEVELOPMENTAL ORIGINS; DNA METHYLATION; SCIENCE; NEUROSCIENCE; SOCIOLOGY; BIOLOGY; RANGE; LIFE; OPPORTUNITIES; EXPECTATIONS;
D O I
10.1080/14636778.2013.861739
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Epigenetics is the study of changes in gene expression caused by mechanisms other than changes in the DNA itself. The field is rapidly growing and being widely promoted, attracting attention in diverse arenas. These include those of the social sciences, where some researchers have been encouraged by the resonance between imaginaries of development within epigenetics and social theory. Yet, sustained attention from science and technology studies (STS) scholars to epigenetics and the praxis it propels has been lacking. In this article, we reflexively consider some of the ways in which epigenetics is being constructed as an area of biomedical novelty and discuss the content and logics underlying the ambivalent promises being made by scientists working in this area. We then reflect on the scope, limits and future of engagements between epigenetics and the social sciences. Our discussion is situated within wider literatures on biomedicine and society, the politics of interventionist STS, and on the problems of caseness within empirical social science.
引用
收藏
页码:429 / 447
页数:19
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