Identification of susceptibility genes for complex metabolic diseases

被引：0
|
作者：
Bogardus, C [1 ]
Baier, L [1 ]
Permana, P [1 ]
Prochazka, M [1 ]
Wolford, J [1 ]
Hanson, R [1 ]
机构：
[1] NIDDKD, Phoenix Epidemiol & Clin Res Branch, NIH, Phoenix, AZ 85016 USA
来源：
LIPIDS AND INSULIN RESISTANCE: THE ROLE OF FATTY ACID METABOLISM AND FUEL PARTITIONING | 2002年 / 967卷
关键词：
Mendelian/non-Mendelian disease; susceptibility genes; genetic; linkage; positional cloning; allele; subphenotype;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
There are few successful attempts to identify genes for common, non-Mendelian diseases such as diabetes, hyperlipidemia, hypertension, etc. Such common disorders are typically both metabolically and genetically complex and the genetic technologies to identify their underlying susceptibility genes are still in their infancy. Nonetheless, genetic strategies have emerged that, when the technologies are fully developed, should allow similar success rates as for Mendelian diseases.
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页码：1 / 6
页数：6
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