Succinylated alkaline phosphatase is a potent lipopolysaccharide (LPS) dephosphorylating enzyme and reduces intrahepatic inflammatory response in mice challenged with LPS.

被引：0
|
作者：
Poelstra, K [1 ]
Grasmeijer, R [1 ]
Meijer, DKF [1 ]
机构：
[1] UNIV GRONINGEN,GRONINGEN UTRECHT INST DRUG EXPLORAT,GRONINGEN,NETHERLANDS
来源：
HEPATOLOGY | 1996年 / 24卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：803 / 803
页数：1
相关论文
共 11 条
  • [1] A single injection of alkaline phosphatase significantly attenuates the inflammatory response upon lipopolysaccharide (LPS) in serum and in livers of mice.
    Poelstra, K
    Verweij, WR
    Bentala, H
    Huizinger-Van der vlag, A
    Meijer, DK
    HEPATOLOGY, 2001, 34 (04) : 279A - 279A
  • [2] Alkaline phosphatase attenuates the response of macrophages upon lipopolysaccharide (LPS); A potential role for this enzyme during cholestasis.
    Poelstra, K
    Bentala, H
    Verweij, WR
    Meijer, DKF
    HEPATOLOGY, 2000, 32 (04) : 198A - 198A
  • [3] Calf intestinal alkaline phosphatase, a novel therapeutic drug for lipopolysaccharide (LPS)-mediated diseases, attenuates LPS toxicity in mice and piglets
    Beumer, C
    Wulferink, M
    Raaben, W
    Fiechter, D
    Brands, R
    Seinen, W
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2003, 307 (02): : 737 - 744
  • [4] Ovarian steroids modulate the systemic inflammatory response OF COWS challenged with lipopolysaccharide (LPS) intrauterine infusion
    Magalhaes, L. Q.
    Barbosa, S. P. F.
    Fagundes, N. S.
    Almeida, M. O.
    Carneiro, L. C.
    Brandao, F. Z.
    Nogueira, G. M.
    Pereira, E. C. M.
    Saut, J. P. E.
    THERIOGENOLOGY, 2022, 182 : 35 - 44
  • [5] Exposure to lipopolysaccharide (LPS) reduces contractile response of small airways from GSTCD-/- mice
    Liu, Bo
    Henry, Amanda P.
    Azimi, Sheyda
    Miller, Suzanne
    Lee, Frank K.
    Lee, Jane C.
    Probert, Kelly
    Kotlikoff, Michael, I
    Sayers, Ian
    Hall, Ian P.
    PLOS ONE, 2019, 14 (09):
  • [6] Kidney-Specific Intestinal Alkaline Phosphatase (IAP) in Transgenic Mice Protects Lipopolysaccharide (LPS)-Induced Inflammation and Renal Failure
    Ghosh, Siddhartha S.
    Gipson, Graham T.
    Kang, Joshua M.
    Ghosh, Shobha
    Gehr, Todd W.
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2021, 32 (10): : 162 - 162
  • [7] Maresin 1 alleviates the inflammatory response, reduces oxidative stress and protects against cardiac injury in LPS-induced mice
    Li, Dan
    Wang, Menglong
    Ye, Jing
    Zhang, Jishou
    Xu, Yao
    Wang, Zhen
    Zhao, Mengmeng
    Ye, Di
    Wan, Jun
    LIFE SCIENCES, 2021, 277
  • [8] The Anti-Inflammatory Effect of Trichilia martiana C. DC. in the LipopolysaccharideStimulated Inflammatory Response in Macrophages and Airway Epithelial Cells and in LPS-Challenged Mice
    Park, Ji-Won
    Ryu, Hyung Won
    Ahn, Hye In
    Min, Jae-Hong
    Kim, Seong-Man
    Kim, Min-Gu
    Kwon, Ok-Kyoung
    Hwang, Daseul
    Kim, Soo-Yong
    Choi, Sangho
    Zamora, Nelson
    Rosales, Kattia
    Oh, Sei-Ryang
    Lee, Jae-Won
    Ahn, Kyung-Seop
    JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2020, 30 (11) : 1614 - 1625
  • [9] Protein-energy malnutrition decreases the expression of TLR-4/MD-2 and CD14 receptors in peritoneal macrophages and reduces the synthesis of TNF-α in response to lipopolysaccharide (LPS) in mice
    Fock, Ricardo Ambrosio
    Vinolo, Marco Aurelio Ramirez
    de Moura Sa Rocha, Vanessa
    de Sa Rocha, Luiz Carlos
    Borelli, Primavera
    CYTOKINE, 2007, 40 (02) : 105 - 114
  • [10] Decreased Levels of Triggering Receptor Expressed on Myeloid Cells-Like (TREM-like) Transcript-1 (TLT-1) Are Present in Cord Blood from Premature Infants, and Deficiency in Mice Promotes the In-Utero Inflammatory Response to Maternal Systemic Lipopolysaccharide (LPS) Exposure.
    Garcia, Paola E. Pena
    Morales-Ortiz, Jessica
    Finette, Barry A.
    Washington, Anthony V.
    Bonney, Elizabeth A.
    REPRODUCTIVE SCIENCES, 2021, 28 (SUPPL 1) : 216A - 217A
12