Management of Painful Bone Metastases: Our Experience According to Scientific Evidence on Palliative Radiotherapy

被引：0

作者：

Di Franco, Rossella ^{[1
]}

Falivene, Sara ^{[1
]}

Ravo, Vincenzo ^{[2
]}

Mammucari, Massimo ^{[3
]}

Sarli, Ennio ^{[3
]}

Baffini, Stella ^{[4
]}

De Palma, Giampaolo ^{[2
]}

Pepe, Alfonsina ^{[5
]}

Traettino, Marianna ^{[1
]}

Muto, Matteo ^{[5
]}

Cappabianca, Salvatore ^{[1
]}

Muto, Paolo ^{[2
]}

机构：

[1] Univ Naples 2, I-80131 Naples, Italy

[2] Ist Nazl Studio & Cura Tumori Fdn Giovanni Pascal, Naples, Italy

[3] Local Hlth Syst RMF, Primary Care, Rome, Italy

[4] PLS, Florence, Italy

[5] Mutoonlus Fdn Naples, Naples, Italy

来源：

ANTICANCER RESEARCH | 2014年 / 34卷 / 02期

关键词：

Radiotherapy; fractionation; bone metastases; pain; rapid-onset opioids;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Aim: Our aim was to evaluate retrospectively the role of the radiotherapy in the multi-disciplinary management of pain due to bone metastases. Patients and Methods: A total of 305 patients received radiotherapy with or without bisphosphonate and antalgic drugs. Tolerability and efficacy were evaluated using a Numerical Rating Scale, Pain Intensity Difference evaluation scale related to administration of the drug, a 5-point verbal scale of the patients' general impression. Results: We found differences in some patient subgroups: pain reduction was significantly more evident in patients treated with a single-fraction radiotherapy scheme. Overall, 68% of patients experienced an improvement in pain control using concomitant drugs during radiotherapy. Conclusion: Our study underlines the role of radiotherapy in the management of metastatic bone pain. The use of rapid-onset opioids to prevent predictable pain is a crucial step in managing radiotherapy. An interdisciplinary approach is recommended.

引用

页码：1011 / 1014

页数：4

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