Zygote versus embryo transfer: A prospective randomized multicenter trial

被引：12

作者：

Dale, D ^{[1
]}

Fiorentino, A ^{[1
]}

de Simone, ML ^{[1
]}

di Matteo, L ^{[1
]}

di Frega, AS ^{[1
]}

Wilding, M ^{[1
]}

Fehr, P ^{[1
]}

Bassan, E ^{[1
]}

Lo Giudice, C ^{[1
]}

Maselli, A ^{[1
]}

Cappiello, F ^{[1
]}

Zullo, F ^{[1
]}

机构：

[1] Clin Villa Del Sole, Ctr Reprod Biol, Naples, Italy

来源：

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS | 2002年 / 19卷 / 10期

关键词：

human oocyte; intracytoplasmic sperm injection; in vitro fertilisation;

D O I：

10.1023/A:1020354318164

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Purpose: To determine the efficiency of transferring human zygotes as opposed to human day 2 or 3 embryos. Methods: A prospective, randomized, Multicenter trial. Patients were randomized into zygote or embryo transfer. Patients were prepared for oocyte retrieval using standardized protocols. Oocyte retrieval was performed under general anesthesia. Oocytes and spermatozoa were treated using standard laboratory techniques. All protocols were coordinated by the coordinating center. Results: A total of 386 patients were included in the trial. Pregnancy rates were 36.5% after zygote transfer and 42% after embryo transfer. Implantation rates were equivalent (17%) in both groups. Conclusions: No general difference was observed for zygote or embryo transfer. The results suggest that zygote transfer is a valid alternative to embryo transfer.

引用

页码：456 / 461

页数：6

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