The role of energy and fat in cancers of the breast and colon-rectum in a Southern European population

被引:29
|
作者
Franceschi, S [1 ]
Favero, A [1 ]
机构
[1] Ctr Riferimento Oncol, Serv Epidemiol, I-33081 Aviano, Italy
关键词
breast cancer; case-control study; colorectal cancer; diet; fat;
D O I
10.1023/A:1008384302955
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: Several uncertainties remain with respect to the role of intake of fat and/or total energy in the etiology of cancer of the breast and colon-rectum. Patients and Methods.. Between 1991 and 1996, 2569 women with incident breast cancer (median age: 55 years), 1953 subjects with cancer of the colon-rectum (median age = 62), and 5155 hospital controls were interviewed in six Italian areas. The validated food frequency questionnaire included questions on 78 foods and recipes and specific questions on individual fat intake pattern. Results. Significant trends of increasing breast and colorectal cancer risk with increasing intake emerged for bread and pasta, pork and processed meats and potatoes (breast cancer only), cakes and desserts (colon-rectum cancers only), and refined sugar. Most vegetables were inversely associated with cancer of the colon and rectum, whereas only carrots and raw vegetables seemed to lower breast cancer risk. High fruit intake was associated only with a reduction of rectal cancer. Total energy intake was directly associated with all cancer sites. Among macronutrients, high intake of starch and saturated fat seemed to lead to an increase of cancer risk. High intakes of polyunsaturated fatty acids (chiefly derived from olive oil and seed oils) were protective. Among micronutrients, beta-carotene, vitamin E, and calcium showed inverse associations with breast and colorectal cancer risk. Conclusions: An excess of energy intake, particularly from refined bread and pasta, can be an unfavourable feature of the Mediterranean diet, in the presence of a sedentary lifestyle.
引用
收藏
页码:61 / 63
页数:3
相关论文
共 32 条
  • [1] MULTIPLE SYNCHRONOUS CANCERS OF COLON-RECTUM
    PIHL, B
    WENCKERT, A
    EKELUND, G
    [J]. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 1972, 7 : 18 - &
  • [2] Energy sources and risk of cancer of the breast and colon-rectum in Italy
    Favero, D
    Parpinel, M
    Montella, M
    [J]. ADVANCES IN NUTRITION AND CANCER 2, 1999, 472 : 51 - 55
  • [3] ALCOHOL AND THE RISK OF CANCERS OF THE STOMACH AND COLON-RECTUM
    FRANCESCHI, S
    LAVECCHIA, C
    [J]. DIGESTIVE DISEASES, 1994, 12 (05) : 276 - 289
  • [4] Tetrachloroethylene-contaminated drinking water in Massachusetts and the risk of colon-rectum, lung, and other cancers
    Paulu, C
    Aschengrau, A
    Ozonoff, D
    [J]. ENVIRONMENTAL HEALTH PERSPECTIVES, 1999, 107 (04) : 265 - 271
  • [5] Chlorinated drinking water exposure and bladder and colon-rectum cancers in the province of Modena (Northern Italy): An ecological study
    Righi, E.
    Fantuzzi, G.
    Biggeri, A.
    Aggazzotti, G.
    [J]. EPIDEMIOLOGY, 2006, 17 (06) : S325 - S326
  • [6] Dental visits and colon-rectum cancer: A nationwide population-based nested case-control study in Taiwan
    Liu, Fu-Hsuan
    Huang, Jing-Yang
    Chang, Yu-Chao
    [J]. JOURNAL OF DENTAL SCIENCES, 2024, 19 (01) : 601 - 606
  • [7] The role of DNA testing in breast, ovarian, and colon cancers
    Friedrich, CA
    [J]. AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 2003, 325 (03): : 120 - 124
  • [8] Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study
    Ureyen, Orhan
    Ulusoy, Cemal
    Acar, Atahan
    Saglam, Fazil
    Kiziloglu, Ilker
    Alemdar, Ali
    Atahan, Kemal Murat
    Dadali, Emrah
    Karaisli, Serkan
    Aydin, Mehmet Can
    Ilhan, Enver
    Guven, Hakan
    [J]. TURKISH JOURNAL OF SURGERY, 2020, 36 (01) : 23 - 32
  • [9] Dietary Fibre Intake and Risks of Cancers of the Colon and Rectum in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Murphy, Neil
    Norat, Teresa
    Ferrari, Pietro
    Jenab, Mazda
    Bueno-de-Mesquita, Bas
    Skeie, Guri
    Dahm, Christina C.
    Overvad, Kim
    Olsen, Anja
    Tjonneland, Anne
    Clavel-Chapelon, Francoise
    Boutron-Ruault, Marie Christine
    Racine, Antoine
    Kaaks, Rudolf
    Teucher, Birgit
    Boeing, Heiner
    Bergmann, Manuela M.
    Trichopoulou, Antonia
    Trichopoulos, Dimitrios
    Lagiou, Pagona
    Palli, Domenico
    Pala, Valeria
    Panico, Salvatore
    Tumino, Rosario
    Vineis, Paolo
    Siersema, Peter
    van Duijnhoven, Franzel
    Peeters, Petra H. M.
    Hjartaker, Anette
    Engeset, Dagrun
    Gonzalez, Carlos A.
    Sanchez, Maria-Jose
    Dorronsoro, Miren
    Navarro, Carmen
    Ardanaz, Eva
    Quiros, Jose R.
    Sonestedt, Emily
    Ericson, Ulrika
    Nilsson, Lena
    Palmqvist, Richard
    Khaw, Kay-Tee
    Wareham, Nick
    Key, Timothy J.
    Crowe, Francesca L.
    Fedirko, Veronika
    Wark, Petra A.
    Chuang, Shu-Chun
    Riboli, Elio
    [J]. PLOS ONE, 2012, 7 (06):
  • [10] Role of different types of vegetables and fruit in the prevention of cancer of the colon, rectum, and breast
    Franceschi, S
    Parpinel, M
    La Vecchia, C
    Favero, A
    Talamini, R
    Negri, E
    [J]. EPIDEMIOLOGY, 1998, 9 (03) : 338 - 341