Electrochemical glucose biosensor based on nickel oxide nanoparticle-modified carbon paste electrode

被引：20
|
作者：
Erdem, Ceren [1 ]
Zeybek, Derya Koyuncu [2 ]
Aydogdu, Gozde [1 ]
Zeybek, Bulent [2 ]
Pekyardimci, Sule [1 ]
Kilic, Esma [1 ]
机构：
[1] Ankara Univ, Fac Sci, Dept Chem, TR-906100 Ankara, Turkey
[2] Dumlupinar Univ, Fac Sci & Arts, Dept Chem, Kutahya, Turkey
来源：
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY | 2014年 / 42卷 / 04期
关键词：
amperometric glucose biosensor; carbon paste electrode; glucose oxidase; nickel oxide nanoparticles; ELECTROCATALYTIC ACTIVITY; PLATINUM-ELECTRODE; ASCORBIC-ACID; HUMAN SERUM; IN-VITRO; IMMOBILIZATION; NIO; FILM; NANOTUBE; SENSORS;
D O I：
10.3109/21691401.2013.808649
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
In the present work, we designed an amperometric glucose biosensor based on nickel oxide nanoparticles (NiONPs)-modified carbon paste electrode. The biosensor was prepared by incorporation of glucose oxidase and NiONPs into a carbon paste matrix. It showed good analytical performances such as high sensitivity (367 mu A mmolL(-1)) and a wide linear response from 1.9 x 10(-3) mmolL(-1) to 15.0 mmolL(-1) with a limit of detection (0.11 mu molL(-1)). The biosensor was used for the determination of glucose in human serum samples. The results illustrate that NiONPs have enormous potential in the construction of biosensor for determination of glucose.
引用
收藏
页码：237 / 244
页数：8
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