Microglial activation by prion peptides is enhanced by amyloid associated factors SAP and C1q that increase PrP fibrillarity

被引:0
|
作者
Veerhuis, R
Boshuizen, RS
Morbin, M
Hoozemans, JJ
Eikelenboom, P
机构
[1] Vrije Univ Amsterdam, Med Ctr, Dept Psychiat, Amsterdam, Netherlands
[2] Vrije Univ Amsterdam, Med Ctr, Dept Pathol, Amsterdam, Netherlands
[3] Pepscan Syst BV, Lelystad, Netherlands
[4] Natl Inst Neurol Carlo Besta, Dept Neuropathol, Milan, Italy
关键词
D O I
10.1016/S0197-4580(04)81532-X
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
引用
收藏
页码:S464 / S464
页数:1
相关论文
共 33 条
  • [1] Activation of human microglia by fibrillar prion protein-related peptides is enhanced by amyloid-associated factors SAP and C1q
    Veerhuis, R
    Boshuizen, RS
    Morbin, M
    Mazzoleni, G
    Hoozemans, JJM
    Langedijk, JPM
    Tagliavini, F
    Langeveld, JPM
    Eikelenboom, P
    NEUROBIOLOGY OF DISEASE, 2005, 19 (1-2) : 273 - 282
  • [2] C1q, the Recognition Subcomponent of the Classical Pathway of Complement, Drives Microglial Activation
    Faerber, Katrin
    Cheung, Giselle
    Mitchell, Daniel
    Wallis, Russell
    Weihe, Eberhard
    Schwaeble, Wilhelm
    Kettenmann, Helmut
    JOURNAL OF NEUROSCIENCE RESEARCH, 2009, 87 (03) : 644 - 652
  • [3] Differential regulation of Aβ42-induced neuronal C1q synthesis and microglial activation
    Rong Fan
    Andrea J Tenner
    Journal of Neuroinflammation, 2
  • [4] Differential regulation of Aβ42-induced neuronal C1q synthesis and microglial activation
    Fan, Rong
    Tenner, Andrea J.
    JOURNAL OF NEUROINFLAMMATION, 2005, 2 (1)
  • [5] Amyloid-associated complement factor C1Q and serum amyloid P-component enhance amyloid β- and prion peptide-induced stimulatory effects on human microglia in vitro
    Veerhuis, R
    Gerritsen, WH
    Boshuizen, RS
    Tagliavini, F
    Eikelenboom, P
    MOLECULAR IMMUNOLOGY, 2003, 40 (2-4) : 187 - 188
  • [6] C1q propagates microglial activation and neurodegeneration in the visual axis following retinal ischemia/reperfusion injury
    Sean M. Silverman
    Byung-Jin Kim
    Garreth R. Howell
    Joselyn Miller
    Simon W. M. John
    Robert J. Wordinger
    Abbot F. Clark
    Molecular Neurodegeneration, 11
  • [7] C1q propagates microglial activation and neurodegeneration in the visual axis following retinal ischemia/reperfusion injury
    Silverman, Sean M.
    Kim, Byung-Jin
    Howell, Garreth R.
    Miller, Joselyn
    John, Simon W. M.
    Wordinger, Robert J.
    Clark, Abbot F.
    MOLECULAR NEURODEGENERATION, 2016, 11
  • [8] Preferential uptake of amyloid beta 1-42 oligomers by primary human astrocytes in vitro: Influence of SAP and C1q
    Nielsen, H. M.
    Mulder, S. D.
    Veerhuis, R.
    MOLECULAR IMMUNOLOGY, 2009, 46 (14) : 2860 - 2860
  • [9] Amyloid β plaque-associated proteins C1q and SAP enhance the Aβ1–42 peptide-induced cytokine secretion by adult human microglia in vitro
    Robert Veerhuis
    Mariëlle J. Van Breemen
    Jeroen J. Hoozemans
    Michela Morbin
    Jamal Ouladhadj
    Fabrizio Tagliavini
    Piet Eikelenboom
    Acta Neuropathologica, 2003, 105 : 135 - 144
  • [10] C1Q BINDING AND COMPLEMENT ACTIVATION BY HUMAN C-REACTIVE PROTEIN (CRP) PEPTIDES AND RECOMBINANT CRP
    JIANG, H
    YING, SC
    GUPTA, K
    GEWURZ, H
    JOURNAL OF IMMUNOLOGY, 1993, 150 (08): : A224 - A224