A pilot study of a nurse-delivered cognitive behavioral therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa

被引:56
|
作者
Andersen, Lena S. [1 ]
Magidson, Jessica F. [2 ]
O'Cleirigh, Conall [2 ,3 ]
Remmert, Jessica E. [2 ]
Kagee, Ashraf [4 ]
Leaver, Matthew [1 ]
Stein, Dan J. [1 ,5 ]
Safren, Steven A. [6 ]
Joska, John [1 ]
机构
[1] Univ Cape Town, Cape Town, South Africa
[2] Harvard Med Sch, Massachusetts Gen Hosp, Boston, MA USA
[3] Fenway Hlth, Boston, MA USA
[4] Stellenbosch Univ, Stellenbosch, South Africa
[5] MRC, Unit Anxiety & Stress Disorders, Stellenbosch, Western Cape, South Africa
[6] Univ Miami, Coral Gables, FL 33124 USA
基金
英国医学研究理事会; 英国惠康基金;
关键词
adherence; cognitive behavioral therapy; depression; HIV; low- and middle-income countries; South Africa; task-sharing; RANDOMIZED CONTROLLED-TRIAL; CBT-AD; ANTIRETROVIRAL THERAPY; INFECTED INDIVIDUALS; INCOME COUNTRIES; RATING-SCALE; HIV/AIDS; HEALTH; DISORDERS; METAANALYSIS;
D O I
10.1177/1359105316643375
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Depression is prevalent among people living with HIV in South Africa and interferes with adherence to antiretroviral therapy. This study evaluated a nurse-delivered, cognitive behavioral therapy intervention for adherence and depression among antiretroviral therapy users with depression in South Africa (n = 14). Primary outcomes were depression, antiretroviral therapy adherence, feasibility, and acceptability. Findings support robust improvements in mood through a 3-month follow up. Antiretroviral therapy adherence was maintained during the intervention period. Participant retention supports acceptability; however, modest provider fidelity despite intensive supervision warrants additional attention to feasibility. Future effectiveness research is needed to evaluate this nurse-delivered cognitive behavioral therapy intervention for adherence and depression in this context.
引用
收藏
页码:776 / 787
页数:12
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