PrepMS: TOF MS data graphical preprocessing tool

被引:32
|
作者
Karpievitch, Yuliya V. [1 ]
Hill, Elizabeth G.
Smolka, Adam J.
Morris, Jeffrey S.
Coombes, Kevin R.
Baggerly, Keith A.
Almeida, Jonas S.
机构
[1] Med Univ S Carolina, Dept Biostat Bioinformat & Epidemiol, Charleston, SC 29425 USA
[2] Med Univ S Carolina, Dept Med, Charleston, SC 29425 USA
[3] Univ Texas, MD Anderson Canc Ctr, Dept Biostat & Appl Math, Houston, TX 77030 USA
关键词
D O I
10.1093/bioinformatics/btl583
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We introduce a simple-to-use graphical tool that enables researchers to easily prepare time-of-flight mass spectrometry data for analysis. For ease of use, the graphical executable provides default parameter settings, experimentally determined to work well in most situations. These values, if desired, can be changed by the user. PrepMS is a stand-alone application made freely available (open source), and is under the General Public License (GPL). Its graphical user interface, default parameter settings, and display plots allow PrepMS to be used effectively for data preprocessing, peak detection and visual data quality assessment.
引用
收藏
页码:264 / 265
页数:2
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