Organocatalytic Enantio- and Diastereoselective Assembly of Thiazolidine Scaffolds by Formal [3+2] Annulation

被引：22
|
作者：
Qian, Hui [1 ]
Sun, Jianwei [1 ]
机构：
[1] Hong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R China
来源：
ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2014年 / 3卷 / 04期
关键词：
annulation; cinchona alkaloids; organocatalysis; quinidines; thiazolidines; ENANTIOSELECTIVE SYNTHESIS; FACILE SYNTHESIS;
D O I：
10.1002/ajoc.201400025
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An organocatalytic enantio- and diastereoselective formal [3+2] annulation between imines and 1,4-dithiane-2,5-diol is disclosed. The reaction provides rapid access to chiral thiazolidine-based molecules starting from a readily available catalyst and achiral starting materials.
引用
收藏
页码：387 / 390
页数：4
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