Outcomes of Elderly Patients Undergoing Emergency Surgery for Complicated Colorectal Cancer: A Retrospective Cohort Study

被引:12
|
作者
Metidieri Menegozzo, Carlos Augusto [1 ]
Teixeira-Junior, Frederico [1 ]
do Couto-Netto, Sergio Dias [1 ]
Martins-Junior, Octacilio [1 ]
Bernini, Celso de Oliveira [1 ]
Utiyama, Edivaldo Massazo [1 ]
机构
[1] Univ Sao Paulo, Hosp Clin HCFMUSP, Fac Med, Div Cirurgia Geral & Trauma, Sao Paulo, SP, Brazil
关键词
Colorectal Neoplasms; Colorectal Surgery; Postoperative Complications; Elderly; Emergency Treatment; General Surgery; Surgical Oncology; RISK-FACTORS; LEFT COLON; LONG-TERM; MORTALITY; RESECTION;
D O I
10.6061/clinics/2019/e1074
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE: Colorectal cancer is one of the most frequent types of malignant neoplasms. Age is a risk factor for this disease, with 75% of cases diagnosed in patients older than 65 years. Complications such as obstruction, hemorrhage, and perforation are present in more than one-third of cases and require emergency treatment. We aim to analyze the profile of elderly patients undergoing surgery for complicated colorectal cancer, and to evaluate factors related to worse short-term prognosis. METHODS: A retrospective analysis of patients who underwent emergency surgical treatment for complicated colorectal cancer was performed. Demographics, clinical, radiological and histological data were collected. RESULTS: Sixty-seven patients were analyzed. The median age was 72 years, and almost half (46%) of the patients were female. Obstruction was the most prevalent complication at initial presentation (72%). The most common sites of neoplasia were the left and sigmoid colon in 22 patients (32.8%), and the right colon in 17 patients (25.4%). Resection was performed in 88% of cases, followed by primary anastomosis in almost half. The most frequent clinical stages were II (48%) and III (22%). Forty-three patients (65.7%) had some form of postoperative complication. Clavien-Dindo grades 1, 2, and 4, were the most frequent. Complete oncologic resection was observed in 80% of the cases. The thirty-day mortality rate was 10.4%. Advanced age was associated with worse morbidity and mortality. CONCLUSION: Elderly patients with complicated colorectal cancer undergoing emergency surgery have high morbidity and mortality rates. Advanced age is significantly associated with worse outcomes.
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页数:6
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