Fluconazole-carbamazepine interaction

被引：0
|
作者：
Finch, CK
Green, CA
Self, TH
机构：
[1] Univ Tennessee, Hlth Sci Ctr, Dept Clin Pharm, Memphis, TN 38163 USA
[2] Univ Tennessee, Hlth Sci Ctr, Dept Internal Med, Memphis, TN USA
来源：
SOUTHERN MEDICAL JOURNAL | 2002年 / 95卷 / 09期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The patient we describe had elevated carbamazepine serum concentrations during concomitant fluconazole administration (400 mg/day), including serial concentrations both before and after antifungal therapy. Since fluconazole is a known inhibitor of the cytochrome P-450 enzyme system, this suggests an inhibition of carbamazepine metabolism.
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页码：1099 / 1100
页数：2
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