The role of BOLD-fMRI in elucidating migraine pathophysiology

被引:15
|
作者
Tedeschi, G. [1 ,2 ]
Russo, A. [1 ,2 ]
Conte, F. [1 ]
Salemi, F. [1 ]
Tessitore, A. [1 ]
机构
[1] Univ Naples 2, Dept Neurol, Headache Ctr, Naples, Italy
[2] Inst Diag & Care Hermitage Capodimonte, Naples, Italy
关键词
Functional magnetic resonance; Blood oxygenation level dependent; fMRI; BOLD; Migraine; FUNCTIONAL MRI-BOLD; SPREADING DEPRESSION; VISUAL-STIMULATION; BRAIN; ACTIVATION; AURA; PAIN;
D O I
10.1007/s10072-013-1383-z
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Migraine is a neurologic disorder characterized by disabling attacks of throbbing headache with specific features and associated symptoms. Despite the recent discoveries in basic neurosciences, migraine pathophysiology is not completely understood. Nevertheless, in the last decades, advances in functional magnetic resonance imaging (fMRI) have significantly provided new insights into migraine mechanisms. Blood oxygen level dependent (BOLD) fMRI technique is the most commonly used method to explore brain function and connectivity due to high temporal and spatial resolution. The purpose of this review is to present a synthesis of recent BOLD-fMRI studies which have allowed us to elucidate the complex process involved in migraine pathophysiology.
引用
收藏
页码:S47 / S50
页数:4
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