Study of DNA Complexes with Platinum Coordination Compounds using Atomic Force and Fluorescent Microscopy

被引：0
|
作者：
Sharikhina, Yu, V [1 ]
Kasyanenko, N. A. [2 ]
机构：
[1] St Petersburg Min Univ, St Petersburg, Russia
[2] St Petersburg State Univ, St Petersburg, Russia
来源：
INTERNATIONAL CONFERENCE ON APPLIED PHYSICS, POWER AND MATERIAL SCIENCE | 2019年 / 1172卷
关键词：
calf thymus DNA; platinum compounds; dimethyl sulfoxide; AFM; fluorescent microscopy; CISPLATIN;
D O I：
10.1088/1742-6596/1172/1/012107
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Experiment demonstrates that DNA interaction with Pten show tendency to appearance of DNA bending, similar to that observed for cisDDP. Atomic Force Microscopy (AFM) images indicate the existence of intra- and interstrand for DNA-Pten (DMSO) complexes.
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页数：6
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