The Role of the Microbiology Laboratory in Antimicrobial Stewardship Programs

被引:31
|
作者
Avdic, Edina [1 ]
Carroll, Karen C. [2 ,3 ]
机构
[1] Johns Hopkins Univ Hosp, Dept Pharm, Baltimore, MD 21287 USA
[2] Johns Hopkins Univ, Sch Med, Dept Pathol, Baltimore, MD 21287 USA
[3] Johns Hopkins Univ, Sch Med, Dept Med, Baltimore, MD 21287 USA
关键词
Antimicrobial stewardship; Microbiology laboratory; Rapid diagnostics; Antibiogram; Procalcitonin; RESPIRATORY-TRACT INFECTIONS; DESORPTION IONIZATION-TIME; FLIGHT MASS-SPECTROMETRY; IN-SITU HYBRIDIZATION; POSITIVE BLOOD CULTURES; INTENSIVE-CARE PATIENTS; GUIDED ANTIBIOTIC USE; PROCALCITONIN-GUIDANCE; DISEASES SOCIETY; THERAPY;
D O I
10.1016/j.idc.2014.01.002
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
One of the impediments to the success of antimicrobial stewardship is the lack of availability of rapid and sensitive laboratory tests. The last decade has seen an explosion in new technologies that permit, in less than 4 hours, the identification of organisms and their resistance markers. In addition, the use of biomarkers has been explored in algorithms to distinguish infections that require antimicrobial agents. Clinical microbiology laboratories also contribute to the success of stewardship programs through compilation of aggregate antimicrobial susceptibility data. This article reviews rapid diagnostics, the use of biomarkers, and antibiogram development to antimicrobial stewardship activities and the subsequent impact on patient outcomes.
引用
收藏
页码:215 / +
页数:22
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