Educational no.5: next-generation gene panel sequencing

被引：0

作者：

Kranewitter, Wolfgang ^{[1
]}

机构：

[1] Ordensklinikum Linz Barmherzige Schwestern, Labor Mol Biol & Tumorzytogenet, Seilerstatte 4, A-4010 Linz, Austria

来源：

MEMO-MAGAZINE OF EUROPEAN MEDICAL ONCOLOGY | 2019年 / 12卷 / 02期

关键词：

Next-generation sequencing; Libarary preparation; Variant interpretation; Bioinformatic analysis; Hemato-oncology; JOINT-CONSENSUS-RECOMMENDATION; ASSOCIATION; GUIDELINES; STANDARDS; VARIANTS; COLLEGE;

D O I：

10.1007/s12254-019-0479-4

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Next-generation sequencing allows the simultaneous interrogation of a large number of genomic targets and is therefore highly suitable for situations, in which mutations in many different genes may have a clinical impact. This short educational discusses the process from the sample to the reported mutations and the limits of the method.

引用

页码：111 / 114

页数：4

共 50 条

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Wolfgang Kranewitter
[J]. memo - Magazine of European Medical Oncology, 2019, 12 : 111 - 114
[2] A TARGETED NEXT-GENERATION SEQUENCING GENE PANEL FOR AUTOINFLAMMATION
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