Autoimmune hepatitis overlapping with primary sclerosing cholangitis

被引:8
|
作者
Takiguchi, J [1 ]
Ohira, H [1 ]
Rai, T [1 ]
Shishido, S [1 ]
Tojo, J [1 ]
Sato, Y [1 ]
Kasukawa, R [1 ]
Watanabe, H [1 ]
Funabashi, Y [1 ]
Kumakawa, H [1 ]
机构
[1] Fukushima Med Univ, Sch Med, Dept Internal Med 2, Fukushima 9601295, Japan
关键词
AIH; PSC; endoscopic retrograde cholangiograph; prednisone; azathioprine; ursodeoxycholic acid;
D O I
10.2169/internalmedicine.41.696
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A case of autoimmune hepatitis (AIH) complicated by primary sclerosing cholangitis (PSC) in a 36-year-old woman is reported. AIH overlapping with PSC has been rarely reported, and to the best of our knowledge, there have been no reports in Japan. Based on the criteria for diagnosis of AIH and on typical endoscopic retrograde cholangiograph (ERC) findings, the patient was diagnosed as having AIH overlapping with PSC. Her transaminase levels normalized within 1 month after administration of prednisone, azathioprine and ursodeoxycholic acid, but her cholestatic enzyme level remained elevated. The effect of treatment on the cholestatic features is thought to be an important factor for predicting the prognosis of AIH overlapping with PSC.
引用
收藏
页码:696 / 700
页数:5
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