Targeting prostate cancer with the CDK4 and CDK6 inhibitor abemaciclib

被引:3
|
作者
Torres-Guzman, Raquel [1 ]
Baquero, Carmen [1 ]
Patricia Ganado, Maria [1 ]
Marugan, Carlos [1 ]
Bian, Huimin [1 ]
Zeng, Yi [1 ]
Rama, Ramon [1 ]
Du, Jian [1 ]
Jose Lallena, Maria [1 ]
机构
[1] Eli Lilly, Alcobendas, Spain
关键词
D O I
10.1158/1538-7445.AM2020-4850
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
4850
引用
收藏
页数:2
相关论文
共 50 条
  • [1] The identification of combinations for the CDK4 and CDK6 inhibitor, abemaciclib
    Gong Xueqian
    Chio, Li-Chun
    Webster, Yue
    Lallena, Maria Jose
    Boehnke, Karsten
    Torres, Raquel
    Iversen, Phil
    De Dios, Alfonso
    Smith, Ian
    Reinhard, Christoph
    Peng, Sheng-Bin
    Dempsey, Jack
    Burke, Teresa
    Chen, Shih-Hsun
    Stewart, Trent
    Beckmann, Richard
    Wu, Wenjuan
    Buchanan, Sean G.
    [J]. MOLECULAR CANCER RESEARCH, 2016, 14
  • [2] Abemaciclib, a CDK4 and CDK6 inhibitor for the treatment of metastatic breast cancer
    Martin, Miguel
    Garcia-Saenz, Jose A.
    Manso, Luis
    Llombart, Antonio
    Cassinello, Alejo
    Atienza, Manuel
    Ringeisen, Francois
    Ciruelos, Eva
    [J]. FUTURE ONCOLOGY, 2020, 16 (33) : 2763 - 2778
  • [3] Targeting CDK4 and CDK6 in cancer
    Shom Goel
    Johann S. Bergholz
    Jean J. Zhao
    [J]. Nature Reviews Cancer, 2022, 22 : 356 - 372
  • [4] Targeting CDK4 and CDK6 in cancer
    Goel, Shom
    Bergholz, Johann S.
    Zhao, Jean J.
    [J]. NATURE REVIEWS CANCER, 2022, 22 (06) : 356 - 372
  • [5] Molecular features that determine the sensitivity of cancer cells to abemaciclib, an inhibitor of CDK4 and CDK6
    Gong, Xuegian
    Chio, Li -Chun
    Lallena, MaryJo
    Merzoug, Farhana
    Chu, Shaoyou
    Webster, Yue
    Dempsey, Jack
    Ma, Xiwen
    De Dios, Alfonso
    Beckman, Richard
    Buchanan, Sean G.
    [J]. CANCER RESEARCH, 2015, 75
  • [6] The major human metabolites of abemaciclib are inhibitors of CDK4 and CDK6
    Burke, Teresa
    Torres, Raquel
    McNulty, Ann
    Dempsey, Jack
    Kolis, Stanley
    Kulanthaivel, Palaniappan
    Beckmann, Richard
    [J]. CANCER RESEARCH, 2016, 76
  • [7] Targeting CDK4 and CDK6: From Discovery to Therapy
    Sherr, Charles J.
    Beach, David
    Shapiro, Geoffrey I.
    [J]. CANCER DISCOVERY, 2016, 6 (04) : 353 - 367
  • [8] PALBOCICLIB Cyclin CDK4/CDK6 Inhibitor Oncolytic
    Haddley, K.
    [J]. DRUGS OF THE FUTURE, 2013, 38 (11) : 745 - 755
  • [9] Targeting Non-Kinase Function of CDK6 to Overcome CDK4/6 Inhibitor Resistance
    Alluri, P. G.
    Udden, N.
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2023, 117 (02): : S44 - S44
  • [10] Abemaciclib: The Newest CDK4/6 Inhibitor for the Treatment of Breast Cancer
    Palumbo, Alison
    Lau, Gary
    Saraceni, Megan
    [J]. ANNALS OF PHARMACOTHERAPY, 2019, 53 (02) : 178 - 185