Total synthesis of the Securinega alkaloids

被引：64
|
作者：
Weinreb, Steven M. [1 ]
机构：
[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA
来源：
NATURAL PRODUCT REPORTS | 2009年 / 26卷 / 06期
基金：
美国国家卫生研究院; 美国国家科学基金会;
关键词：
SUFFRUTICOSA VAR. AMAMIENSIS; ASYMMETRIC-SYNTHESIS; ENANTIOSELECTIVE APPROACH; CONFORMATIONAL-ANALYSIS; DIPOLAR CYCLOADDITION; TRICYCLIC CORE; CHIRAL ALKENES; SECUAMAMINE-A; (-)-NORSECURININE; VIROSECURININE;
D O I：
10.1039/b902265a
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The Securinega alkaloids are a small family of plant metabolites with fascinating bridged tetracyclic structures and significant biological activity. These compounds have drawn increasing interest from synthetic chemists, resulting in a number of innovative total syntheses. This review describes the various synthetic approaches to members of the Securinega family of alkaloids published over the last four decades.
引用
收藏
页码：758 / 775
页数：18
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