Antihypertensive Drugs and Risk of Cancer: Between Scylla and Charybdis

被引：10

作者：

Sanidas, Elias ^{[1
]}

Velliou, Maria ^{[1
]}

Papadopoulos, Dimitrios ^{[1
]}

Fotsali, Anastasia ^{[1
]}

Iliopoulos, Dimitrios ^{[2
]}

Mantzourani, Marina ^{[3
]}

Toutouzas, Konstantinos ^{[4
]}

Barbetseas, John ^{[1
]}

机构：

[1] Laikon Gen Hosp, Hypertens Excellence Ctr ESH, Dept Cardiol, Athens, Greece

[2] Univ Athens, Med Sch, Lab Expt Surg & Surg Res NS Christeas, Athens, Greece

[3] Univ Athens, LAIKO Gen Hosp, Med Sch, Dept Internal Med 1, Athens, Greece

[4] Univ Athens, Hippokrate Hosp, Dept Cardiol 1, Athens, Greece

来源：

AMERICAN JOURNAL OF HYPERTENSION | 2020年 / 33卷 / 12期

关键词：

antihypertensive agents; blood pressure; cancer; hypertension; CALCIUM-CHANNEL BLOCKERS; CONVERTING ENZYME-INHIBITORS; RENIN-ANGIOTENSIN SYSTEM; LONG-TERM USE; WOMEN AGED 55; BREAST-CANCER; MEDICATION USE; BLOOD-PRESSURE; HEPATOCELLULAR-CARCINOMA; HYPERTENSIVE PATIENTS;

D O I：

10.1093/ajh/hpaa098

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Antihypertensive drugs namely angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, calcium channel blockers, beta blockers, and diuretics are among the most clearly documented regimens worldwide with an overall cardioprotective benefit. Given that malignancy is the second leading cause of mortality, numerous observational studies aimed to investigate the carcinogenic potential of these agents with conflicting results. The purpose of this review was to summarize current data in an effort to explore rare side effects and new mechanisms linking antihypertensive drugs with the risk of developing cancer.

引用

页码：1049 / 1058

页数：10

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