Tartaric acid: a natural, green and highly efficient catalyst for the one-pot synthesis of functionalized piperidines

被引：39

作者：

Aboonajmi, Jasem ^{[1
]}

Maghsoodlou, Malek Taher ^{[1
]}

Hazeri, Nourallah ^{[1
]}

Lashkari, Mojtaba ^{[2
]}

Kangani, Mehrnoosh ^{[1
]}

机构：

[1] Univ Sistan & Baluchestan, Dept Chem, Zahedan, Iran

[2] Islamic Azad Univ, Fac Sci, Najafabad Branch, Najafabad, Esfahan, Iran

来源：

RESEARCH ON CHEMICAL INTERMEDIATES | 2015年 / 41卷 / 11期

关键词：

Multi-component reaction; One-pot; Piperidine; Green catalyst; Tartaric acid; No need to column chromatography; MULTICOMPONENT REACTIONS; DIASTEREOSELECTIVE SYNTHESIS; FACILE ACCESS; INHIBITORS; DERIVATIVES; SCAFFOLDS; DESIGN; VIRUS; TETRAHYDROPYRIDINES; GLYCOSYLATION;

D O I：

10.1007/s11164-014-1877-1

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Tartaric acid is a highly effective and efficient catalyst for the one-pot synthesis of highly substituted piperidines through a combination of 1,3-dicarbonyl compounds, aromatic aldehydes, and various amines in methanol at room temperature. The advantages of this protocol are good yields, short reaction time, mild reaction conditions, no need for column chromatography, easy access, simple work-up procedure, and a cheap and biodegradable catalyst.

引用

页码：8057 / 8065

页数：9

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