Endothelial but not Leukocytic 12/15-Lipoxygenase Contributes to Retinal Leukostasis in Diabetic Retinopathy

被引：0
|
作者：
Ibrahim, Ahmed S. [1 ,2 ,3 ]
El-Shafey, Mohamed [4 ]
Saleh, Heba M. [1 ,2 ]
Elmasry, Khaled [1 ,2 ,4 ]
Sheibani, Nader [5 ]
Tawfik, Amany [1 ,2 ]
Al-Shabrawey, Mohamed Al-Sayed [1 ,2 ,6 ]
机构：
[1] Augusta Univ, Oral Biol & Anat, Augusta, GA USA
[2] Augusta Univ, Vis Discovery Inst, Augusta, GA USA
[3] Mansoura Univ, Biochem & Clin Biochem, Augusta, GA USA
[4] Mansoura Univ, Dept Anat, Mansoura, Egypt
[5] Univ Wisconsin Madison, Ophthalmol, Madison, WI USA
[6] Augusta Univ, Cell Biol & Anat, Augusta, GA USA
来源：
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE | 2017年 / 58卷 / 08期
关键词：
D O I：
暂无
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
5215
引用
收藏
页数：3
相关论文
共 50 条
  • [1] 12/15-Lipoxygenase Contributes to Retinal Neuronal Dysfunction in Diabetic Retinopathy
    Moustafa, Mohamed
    Ensley, Andrew
    Ibrahim, Ahmed
    Saul, Alan
    Zhang, Dao-Qi
    Al-Shabrawey, Mohamed Al-Sayed
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2022, 63 (07)
  • [2] 5-lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy
    Gubitosi-Klug, Rose A.
    Talahalli, Ramaprasad
    Du, Yunpeng
    Nadler, Jerry L.
    Kern, Timothy S.
    DIABETES, 2008, 57 (05) : 1387 - 1393
  • [3] Deletion of 12/15-Lipoxygenase Preserves Retinal Neuronal Function in Diabetic Retinopathy
    Wan, Ming
    Ibrahim, Ahmed
    El-Shafey, Mohamed
    Elmasry, Khaled
    Abdulmoneim, Samer
    Saul, Alan
    Al-Shabrawey, Mohamed
    DIABETES, 2018, 67
  • [4] Targeting of 12/15-Lipoxygenase in retinal endothelial cells, but not in monocytes/macrophages, attenuates high glucose-induced retinal leukostasis
    Ibrahim, Ahmed S.
    Saleh, Heba
    El-Shafey, Mohamed
    Hussein, Khaled A.
    El-Masry, Khaled
    Baban, Babak
    Sheibani, Nader
    Wang, Mong-Heng
    Tawfik, Amany
    Al-Shabrawey, Mohamed
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2017, 1862 (06): : 636 - 645
  • [5] 12/15-lipoxygenase contributes to retinal inflammation in diabetic retinopathy via activation of ER stress/NADPH oxidase signaling pathway
    Elmasry, Khaled
    Ibrahim, Ahmed S.
    Saleh, Heba
    Elsherbiny, Nehal
    Elshafey, Sally
    Hussein, Khaled
    Al-Shabrawey, Mohamed Al-Sayed
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2018, 59 (09)
  • [6] 12/15-lipoxygenase and diabetic neuropathy
    Obrosova, Irina G.
    Shin, Jeho
    Lyzogubov, Valeriy V.
    Nadler, Jerry L.
    Drel, Viktor R.
    FASEB JOURNAL, 2007, 21 (06): : A1273 - A1273
  • [7] 12/15-Lipoxygenase Contributes to Neuronal Dysfunction in Diabetic Retinopathy: Unveiling Epigenetic Modification and Cellular Metabolic Shifts
    Moustafa, Mohamed
    Carpenter, Morgan
    Zhang, Xiao
    Zhang, Dao-Qi
    Al-Shabrawey, Mohamed Al-Sayed
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2024, 65 (07)
  • [8] Role for 12/15-lipoxygenase in diabetic neuropathy
    Obrosova, Irina G.
    Lyzogubov, Valeryi
    Marchand, Julie
    Bai, Fulu
    Nadler, Jerry L.
    Drel, Viktor R.
    DIABETES, 2006, 55 : A188 - A188
  • [9] 12/15-lipoxygenase and early diabetic neuropathy
    Obrosova, IG
    Marchand, J
    Nadler, JL
    Drel, VR
    DIABETOLOGIA, 2005, 48 : A356 - A356
  • [10] 12/15-Lipoxygenase inhibitors in diabetic nephropathy in the rat
    Ma, J
    Natarajan, R
    LaPage, J
    Lanting, L
    Kim, N
    Becerra, D
    Clemmons, B
    Nast, CC
    Prakash, GKS
    Mandal, M
    Adler, SG
    PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 2005, 72 (01): : 13 - 20
12345