Conservative and Pharmacologic Treatments for the Diabetic Charcot Foot

被引：15
|
作者：
Petrova, Nina L. [1 ]
Edmonds, Michael E. [1 ]
机构：
[1] Kings Coll Hosp NHS Fdn Trust, Diabet Foot Clin, Denmark Hill, London SE5 9RS, England
来源：
CLINICS IN PODIATRIC MEDICINE AND SURGERY | 2017年 / 34卷 / 01期
关键词：
Charcot neuroarthropathy; Diabetes mellitus; MRI; Casting therapy; Disease activity; ARTHROPATHY; OSTEOARTHROPATHY; NEUROARTHROPATHY; MANAGEMENT; BISPHOSPHONATES; MORTALITY; DISEASE; MARKERS; START;
D O I：
10.1016/j.cpm.2016.07.003
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
Charcot neuroarthropathy is a disabling complication of diabetic neuropathy. Prolonged immobilization in a total contact cast (TCC) is among the main treatments. Education of health care professionals in the application of TCC together with well-conducted clinical trials are required to overcome its frequent underuse. There are no established pharmacologic therapies to treat this condition; however, there is an overwhelming need for a new therapeutic approach. Novel targeted drug delivery systems are required to prevent the pathologic bone and joint destruction of the Charcot neuroarthropathy and this may lead to an improved outcome in diabetic patients with this condition.
引用
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页码：15 / +
页数：11
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