Health-Related Quality of Life in Pediatric Patients with Leukemia in Singapore: A Cross-Sectional Pilot Study

被引:13
|
作者
Choo, Carol C. [1 ]
Chew, Peter K. H. [1 ]
Tan, Pinhong [2 ]
Choo, Jessica Q. [2 ]
Choo, Amanda M. H. [3 ]
Ho, Roger C. [4 ,5 ,6 ,7 ]
Quah, Thuan Chong [2 ]
机构
[1] James Cook Univ, Coll Healthcare Sci, Dept Psychol, Singapore 387380, Singapore
[2] Natl Univ Singapore, Dept Pediat, 1E Kent Ridge Rd, Singapore 119228, Singapore
[3] Univ Cambridge, Sch Clin Med, Cambridge Biomed Campus, Cambridge CB2 0SP, England
[4] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Psychol Med, 1E Kent Ridge Rd, Singapore 119228, Singapore
[5] Natl Univ Singapore, Inst Hlth Innovat & Technol iHealthtech, Singapore 117599, Singapore
[6] Nguyen Tat Thanh Univ, Ctr Excellence Behav Med, Ho Chi Minh City 70000, Vietnam
[7] Huaibei Normal Univ, Fac Educ, 100 Dongshan Rd, Huaibei 235000, Peoples R China
关键词
Leukemia; pediatric; health-related quality of life; age; CHILDREN; ADOLESCENTS; SCHIZOPHRENIA; PEDSQL(TM)-4.0; RELIABILITY; DEPRESSION; ILLNESS; CANCER; SCALES;
D O I
10.3390/ijerph16122069
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
There has been a paradigm shift in health service delivery to a more holistic approach, which considers Quality of Life (QoL) and overall functioning. Health-Related Quality of Life (HRQoL) is a multidimensional construct that encompasses physical functioning as well as psychosocial aspects of emotional and social functioning. This study explored factors related to HRQoL in Asian pediatric patients with leukemia in Singapore. The available variables included: age, treatment duration, household income, gender, ethnicity, religion, diagnosis, and phase of treatment. It is hypothesized that the relationships will be significant. In the current study, there were 60 patients (60% males) with leukemia; their ages ranged from 1 to 21 years (Mean = 8.03, Standard Deviation = 4.55). The hypothesis was partially supported. Age had a significant positive relationship with physical functioning, r(60) = 0.28, p < 0.05, physical health, r(60) = 0.28, p < 0.05, and the total HRQoL score, r(60) = 0.29, p < 0.05. Treatment duration had a positive relationship with school functioning, r(60) = 0.28, p < 0.05. All other correlations were statistically non-significant. The effects of the available psychosocial variables of gender, ethnicity, and religion were examined on scores from the Pediatric Quality of Life Inventory (PedsQL). Ethnicity had a significant effect on social functioning, U = 292.00, p < 0.05, r = 0.3 (medium effect size). Specifically, Chinese (Median = 85.00, n = 33) had significantly higher scores on social functioning than others (Median = 70.00, n = 27). The remaining comparisons were statistically non-significant. The current findings added to QoL research, and provided an impetus for more research in the area of HRQoL for children with leukemia in Singapore.
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页数:9
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