Healthcare resource utilization and costs in amyloid light-chain amyloidosis: a real-world study using US claims data

被引：21
|
作者：
Quock, Tiffany P. [1 ]
Yan, Tingjian [2 ]
Chang, Eunice [2 ]
Guthrie, Spencer [3 ]
Broder, Michael S. [2 ]
机构：
[1] Prothena Biosci Inc, 331 Oyster Point Blvd, San Francisco, CA 94080 USA
[2] Partnership Hlth Analyt Res LLC, 280 S Beverly Dr Ste 404, Beverly Hills, CA 90212 USA
[3] Biopharma Strateg Consulting LLC, 208 2nd Ave, San Francisco, CA 94118 USA
来源：
JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH | 2018年 / 7卷 / 06期
关键词：
AL amyloidosis; healthcare costs; healthcare resource utilization; PRIMARY SYSTEMIC AMYLOIDOSIS; AL AMYLOIDOSIS; CELL TRANSPLANTATION; DEXAMETHASONE; BORTEZOMIB; DIAGNOSIS; BURDEN;
D O I：
10.2217/cer-2017-0100
中图分类号：
R19 [保健组织与事业（卫生事业管理）];
学科分类号：
摘要：
Aim: To estimate healthcare utilization and costs in amyloid light-chain (AL) amyloidosis. Patients & methods: AL amyloidosis patients were identified in 2007-2015 claims databases if they had 1 inpatient/2 outpatient claims consistent with AL amyloidosis and received 1 AL-specific treatment. Descriptive statistics were reported. Results: 50.1% (n=3670) were admitted 1 time during the year, 11.3% (n=827) 3times. From 2007 to2015, bortezomib use increased from 4.6to 25.3%; melphalan use decreased from 18.9to 2.0%; costs increased from 92,866 to $114,030. Among incident patients with at least 2years of follow-up, healthcare utilization and costs decreased from first to second year post-diagnosis. Conclusion: AL chemotherapy-based prescribing practices changed. Total annual healthcare costs increased over time among AL amyloidosis patients.
引用
收藏
页码：549 / 559
页数：11
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