Excess mortality due to COVID-19 in Germany

被引:80
|
作者
Stang, Andreas [1 ,2 ]
Standl, Fabian [1 ]
Kowall, Bernd [1 ]
Brune, Bastian [3 ,4 ]
Boettcher, Juliane [5 ]
Brinkmann, Marcus [6 ]
Dittmer, Ulf [7 ]
Joeckel, Karl-Heinz [1 ]
机构
[1] Univ Hosp Essen, Inst Med Informat Biometry & Epidemiol, Essen, Germany
[2] Boston Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA USA
[3] Med Emergency Serv City Essen, Essen, Germany
[4] Univ Hosp Essen, Dept Trauma Hand & Reconstruct Surg, Essen, Germany
[5] Publ Hlth Dept City Essen, Essen, Germany
[6] Univ Hosp Essen, Ctr Clin Trials, Essen, Germany
[7] Univ Hosp Essen, Inst Virol, Essen, Germany
关键词
Corona virus; COVID-19; Mortality; Pandemic; Germany;
D O I
10.1016/j.jinf.2020.09.012
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Objectives: The first wave of the SARS-CoV-2 pandemic in Germany lasted from week 10 to 23 in 2020. The aim is to provide estimates of excess mortality in Germany during this time. Methods: We analyzed age-specific numbers of deaths per week from 2016 to week 26 in 2020. We used weekly mean numbers of deaths of 2016-2019 to estimate expected weekly numbers for 2020. We estimated standardized mortality ratios (SMR) and 95% confidence intervals. Results: During the first wave observed numbers of deaths were higher than expected for age groups 6069, 80-89, and 90+. The age group 70-79 years did not show excess mortality. The net excess number of deaths for weeks 10-23 was +8,071. The overall SMR was 1.03 (95%CI 1.03-1 .04). The largest increase occurred among people aged 80-89 and 90+ (SMR= 1.08 and SMR= 1.09). A sensitivity analysis that accounts for demographic changes revealed an overall SMR of 0.98 (95%CI 0.98-0.99) and a deficit of 4,926 deaths for week 10-23, 2020. Conclusions: The excess mortality existed for two months. The favorable course of the first wave may be explained by a younger age at infection at the beginning of the pandemic, lower contact rates, and a more efficient pandemic management. (C) 2020 The British Infection Association. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:797 / 801
页数:5
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