Activation of the liver X-receptor (LXR) leads to increased cholesterol excretion into bile and feces independent of Abca1 in mice.

被引：0
|
作者：
Kok, T
Plosch, T
Bloks, VW
Smit, MJ
Havinga, R
Chimini, G
Groen, AK
Kuipers, F
机构：
[1] Univ Groningen Hosp, Ctr Liver Digest & Metab Dis, Groningen, Netherlands
[2] INSERM, CNR, Ctr Immunol, F-13258 Marseille, France
[3] Acad Med Ctr, Dept Gastroenterol, Amsterdam, Netherlands
来源：
HEPATOLOGY | 2002年 / 36卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
718
引用
收藏
页码：342A / 342A
页数：1
相关论文
共 34 条
  • [1] Increased hepatobiliary cholesterol transport by activation of the liver X-receptor LXR is independent of ABCA1 in mice
    Plösch, T
    Kok, T
    Bloks, VW
    Havinga, R
    Smit, MJ
    Chimini, G
    Groen, AK
    Kuipers, F
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2002, 22 (05) : A5 - A5
  • [2] Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1
    Plösch, T
    Kok, T
    Bloks, VW
    Smit, MJ
    Havinga, R
    Chimini, G
    Groen, AK
    Kuiper, F
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (37) : 33870 - 33877
  • [3] ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic mice
    Vaisman, BL
    Lambert, G
    Amar, M
    Joyce, C
    Ito, T
    Shamburek, RD
    Cain, WJ
    Fruchart-Najib, J
    Neufeld, ED
    Remaley, AT
    Brewer, HB
    Santamarina-Fojo, S
    JOURNAL OF CLINICAL INVESTIGATION, 2001, 108 (02): : 303 - 309
  • [4] Peroxisome proliferator-activated receptor δ activation increases intestinal cholesterol excretion in an ABCA1 independent manner
    van der Veen, JN
    Kruit, JK
    Havinga, R
    Baller, JF
    Chimini, G
    Groot, PH
    Groen, AK
    Kuipers, F
    CIRCULATION, 2003, 108 (17) : 72 - 72
  • [5] Induction of ABCA1 expression by liver X receptor (LXR) agonist in renal glomerular mesangial cells
    Guan, T
    Yu, B
    Zhang, YH
    Jackson, CA
    Breyer, MD
    Guan, YF
    FASEB JOURNAL, 2006, 20 (05): : A1467 - A1468
  • [6] Direct Interaction of Nuclear Liver X Receptor-β with ABCA1 Modulates Cholesterol Efflux
    Hozoji, Masako
    Munehira, Youichi
    Ikeda, Yuika
    Makishima, Makoto
    Matsuo, Michinori
    Kioka, Noriyuki
    Ueda, Kazumitsu
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (44) : 30057 - 30063
  • [7] Inhibition of ERK1/2 and Activation of Liver X Receptor Synergistically Induce Macrophage ABCA1 Expression and Cholesterol Efflux
    Zhou, Xiaoye
    Yin, Zhinan
    Guo, Xianzhi
    Hajjar, David P.
    Han, Jihong
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 285 (09) : 6316 - 6326
  • [8] Deficient bile acid synthesis in hyperlipidemic mice enhances HDL-cholesterol via increased hepatic ABCA1 activity
    Princen, HM
    Groenendijk, M
    Post, SM
    Fievet, C
    Staels, B
    Rensen, PC
    CIRCULATION, 2004, 110 (17) : 272 - 272
  • [9] Ttc39b Deficiency Causes an Intestinal Lxr Activation Phenotype With Increased Expression Of Abca1 and HDL-Cholesterol Levels
    Koseki, Masahiro
    Hsieh, Joanne
    Yakushiji, Emi
    Welch, Carrie
    Iqbal, Jahangir
    Hussain, M. Mahmood
    Takiguchi, Shunichi
    Yamashita, Shizuya
    Komuro, Issei
    Rader, Daniel J.
    Tall, Alan R.
    CIRCULATION, 2013, 128 (22)
  • [10] Stigmasterol stimulates transintestinal cholesterol excretion independent of liver X receptor activation in the small intestine
    Lifsey, Hannah C.
    Kaur, Rupinder
    Thompson, Bradley H.
    Bennett, Lisa
    Temel, Ryan E.
    Graf, Gregory A.
    JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2020, 76
1234