Large-scale homologous analysts of genome sequence

被引:0
|
作者
Tang, HX [1 ]
Ding, DF [1 ]
机构
[1] ACAD SINICA,SHANGHAI INST BIOCHEM,SHANGHAI 200031,PEOPLES R CHINA
来源
ACTA BIOCHIMICA ET BIOPHYSICA SINICA | 1996年 / 28卷 / 06期
关键词
genome; large-scale homologous analysis; hashing technique; sparse dynamic programming;
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We described a new method for the large-scale homologous analysis of genome sequences, which used hashing technique combined with sparse dynamic programming to get a sequence alignment. Three examples, the plant chloroplast genomes, the mammalian T-cell receptors C-alpha/C-delta gene loci and the mammalian gamma-crystallin gene clusters were analysed. The results showed that the method was more rapid to obtain accurate enough data and might be useful in genome analysis.
引用
收藏
页码:686 / 693
页数:8
相关论文
共 7 条
  • [1] ALTSCHUL SF, 1990, J MOL BIOL, V215, P403, DOI 10.1006/jmbi.1990.9999
  • [2] CONSTRAINED SEQUENCE ALIGNMENT
    CHAO, KM
    HARDISON, RC
    MILLER, W
    [J]. BULLETIN OF MATHEMATICAL BIOLOGY, 1993, 55 (03) : 503 - 524
  • [3] DUNNEN JT, 1989, GENE, V78, P201
  • [4] EPPESTEIN D, 1992, J ASS COMPUT MATH, V39, P519
  • [5] HOOD L, 1993, GENOMIC ANAL, V5, P63
  • [6] HUANG X, 1991, ADV APPL MATH, V50, P337
  • [7] JORGENSEN JL, 1992, ANNU REV IMMUNOL, V10, P835, DOI 10.1146/annurev.iy.10.040192.004155