Management of the Neck in Well-Differentiated Thyroid Cancer

被引：23

作者：

Asimakopoulos, Panagiotis ^{[1
]}

Shaha, Ashok R. ^{[1
]}

Nixon, Iain J. ^{[2
]}

Shah, Jatin P. ^{[1
]}

Randolph, Gregory W. ^{[3
]}

Angelos, Peter ^{[4
]}

Zafereo, Mark E. ^{[5
]}

Kowalski, Luiz P. ^{[6
,7
]}

Hartl, Dana M. ^{[8
,9
]}

Olsen, Kerry D. ^{[10
]}

Rodrigo, Juan P. ^{[11
,12
,13
]}

Vander Poorten, Vincent ^{[14
,15
]}

Makitie, Antti A. ^{[16
]}

Sanabria, Alvaro ^{[17
,18
,19
]}

Suarez, Carlos ^{[20
,21
]}

Quer, Miquel ^{[22
,23
]}

Civantos, Francisco J. ^{[24
]}

Robbins, K. Thomas ^{[25
]}

Guntinas-Lichius, Orlando ^{[26
]}

Hamoir, Marc ^{[27
]}

Rinaldo, Alessandra ^{[28
]}

Ferlito, Alfio ^{[29
,30
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Head & Neck Serv, 1275 York Ave, New York, NY 10021 USA

[2] Royal Edinburgh Infirm, Dept Otorhinolaryngol Head & Neck Surg, Edinburgh, Midlothian, Scotland

[3] Massachusetts Eye & Ear Infirm, Div Thyroid & Parathyroid Endocrine Surg, Dept Otolaryngol, Boston, MA USA

[4] Univ Chicago, Dept Surg, Chicago, IL 60637 USA

[5] Univ Chicago, MacLean Ctr Clin Med Eth, Chicago, IL 60637 USA

[6] Univ Texas MD Anderson Canc Ctr, Head & Neck Endocrine Surg, Houston, TX 77030 USA

[7] AC Camargo Canc Ctr, Dept Otorhinolaryngol Head & Neck Surg, Sao Paulo, Brazil

[8] Univ Sao Paulo, Dept Head & Neck Surg, Med Sch, Sao Paulo, Brazil

[9] Inst Gustave Roussy, Dept Otolaryngol Head & Neck Surg, Villejuif, France

[10] Lab Phonet & Phonol, Paris, France

[11] Mayo Clin, Dept Otorhinolaryngol, Rochester, MN USA

[12] Hosp Univ Cent Asturias ISPA, Dept Otolaryngol, Oviedo, Spain

[13] Univ Oviedo IUOPA, Oviedo, Spain

[14] CIBERONC, Head & Neck Canc Unit, Madrid, Spain

[15] Univ Hosp Leuven, Dept Otorhinolaryngol Head & Neck Surg, Leuven, Belgium

[16] Sect Head & Neck Oncol, Dept Oncol, Leuven, Belgium

[17] Univ Helsinki, Dept Otorhinolaryngol Head & Neck Surg, Helsinki, Finland

[18] Helsinki Univ Hosp, Helsinki, Finland

[19] Univ Antioquia, Sch Med, Dept Surg, Hosp Univ San Vicente Fdn, Medellin, Colombia

[20] Univ Oviedo, Inst Invest Sanitaria Principado Asturias, ISCIII, Oviedo, Spain

[21] Univ Oviedo, CIBERONC, ISCIII, Oviedo, Spain

[22] Univ Hosp Santa Creu & St Pau, Dept Otolaryngol Head & Neck Surg, Barcelona, Spain

[23] Univ Autonoma Barcelona, Dept Surg, Barcelona, Spain

[24] Univ Miami Miller, Dept Otolaryngol Head & Neck Surg, Sylvester Comprehens Canc Ctr, Sch Med, Miami, FL USA

[25] Southern Illinois Univ, Dept Otolaryngol Head & Neck Surg, Sch Med, Springfield, IL USA

[26] Jena Univ Hosp, ENT Dept, Jena, Germany

[27] UC Louvain, Dept Head & Neck Surg, St Luc Univ Hosp, Brussels, Belgium

[28] King Albert II Canc Inst, Brussels, Belgium

[29] Univ Udine, Sch Med, Udine, Italy

[30] Int Head & Neck Sci Grp, Padua, Italy

来源：

CURRENT ONCOLOGY REPORTS | 2020年 / 23卷 / 01期

关键词：

Lymphatic metastasis; Neck dissection; Thyroid neoplasms; LYMPH-NODE METASTASIS; POSTOPERATIVE THYROGLOBULIN LEVELS; RISK STRATIFICATION; PAPILLARY CARCINOMA; LARYNGEAL NERVE; ADULT PATIENTS; DISSECTION; RECURRENCE; SURGERY; ULTRASOUND;

D O I：

10.1007/s11912-020-00997-6

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Purpose of Review In this narrative review, we discuss the indications for elective and therapeutic neck dissections and the postoperative surveillance and treatment options for recurrent nodal disease in patients with well-differentiated thyroid cancer. Recent Findings Increased availability of advanced imaging modalities has led to an increased detection rate of previously occult nodal disease in thyroid cancer. Nodal metastases are more common in young patients, large primary tumors, specific genotypes, and certain histological types. While clinically evident nodal disease in the lateral neck compartments has a significant oncological impact, particularly in the older age group, microscopic metastases to the central or the lateral neck in well-differentiated thyroid cancer do not significantly affect outcome. As patients with clinically evident nodal disease are associated with worse outcomes, they should be treated surgically in order to reduce rates of regional recurrence and improve survival. The benefit of elective neck dissection remains unverified as the impact of microscopic disease on outcomes is not significant.

引用

页数：12

共 50 条

[1] Management of the Neck in Well-Differentiated Thyroid Cancer
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Ashok R. Shaha
Iain J. Nixon
Jatin P. Shah
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Dana M. Hartl
Kerry D. Olsen
Juan P. Rodrigo
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Antti A. Mäkitie
Alvaro Sanabria
Carlos Suárez
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