Nipah Virus Classification via Fractal Dimension & Shannon Entropy

被引:0
|
作者
Holden, Todd [1 ]
Gadura, N. [2 ]
Cheung, E. [1 ]
Schneider, P. [2 ]
Tremberger, G., Jr. [1 ]
Elham, N. [1 ]
Sunil, D. [1 ]
Lieberman, D. [1 ]
Cheung, T. [1 ]
机构
[1] CUNY Queensborough Community Coll, Dept Phys, New York, NY 11364 USA
[2] CUNY Queensborough Community Coll, Dept Biol, New York, NY 11364 USA
关键词
Nipah virus; glycoprotein; nucleoprotein; Shannon di-nucleotide entropy; fractal dimension; correlation; GENOMES; DNA;
D O I
暂无
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Nipah virus glycoprotein and nucleoprotein sequences were studied using fractal dimension and Shannon entropy. The nucleotide atomic number fluctuation forms the basis of the phylogeny study. The classification reproduces the main results of traditional phylogeny analysis, but with better ability to distinguish closely related strains. The fractal dimension correlation with the GC pair content in the glycoprotein sequence and di-nucleotide entropy in the nucleoprotein suggests different evolutionary mechanisms or strategies. Extension to other flu virus suggests that low fractal dimensionality in the nucleoprotein sequence could be a marker for the Nipah and Spanish-flu-like viruses.
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页数:4
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