CD57+ cells in radicular cyst

被引：25
|
作者：
Moreira, PR
Santos, DFM
Martins, RD
Gomez, RS
机构：
[1] Univ Fed Minas Gerais, Fac Odontol, Sch Dent, Dept Oral Surg & Pathol, BR-30380030 Belo Horizonte, MG, Brazil
[2] Univ Fed Minas Gerais, Dept Restorat Dent, Sch Dent, BR-30380030 Belo Horizonte, MG, Brazil
来源：
INTERNATIONAL ENDODONTIC JOURNAL | 2000年 / 33卷 / 02期
关键词：
immunology; pathogenesis; pathology; radicular cyst;
D O I：
10.1046/j.1365-2591.2000.00276.x
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Aim As CD57 antigen is an important modulator of the immune system, the purpose of the present study was to compare the expression of this antigen on radicular cysts (RC) with hyperplastic or atrophic epithelium. Methodology Twenty cases of RC were retrieved and classified as atrophic or hyperplastic. A biotin-streptavidin amplified system was used for identification of the CD57 receptor. Results The results demonstrated a greater percentage of CD57(+) cells in RC with atrophic epithelium compared to hyperplastic epithelium, Conclusion As the expression of CD57 is indicative of immunosuppression, it may constitute a negative immunomodulator of RC's epithelium growth. Further studies are necessary to understand the importance of this cell to the biological activity or inactivity of RC's epithelium development.
引用
收藏
页码：99 / 102
页数：4
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