New flavonoid and pentacyclic triterpene from Sesamum indicum leaves

被引：10
|
作者：
Nguyen Tien Dat [1 ]
Nguyen Hai Dang [1 ]
Le Nguyen Thanh [1 ]
机构：
[1] Vietnam Acad Sci & Technol, Inst Marine Biochem, Hanoi, Vietnam
来源：
NATURAL PRODUCT RESEARCH | 2016年 / 30卷 / 03期
关键词：
Sesamum indicum; Pedaliaceae; 3-epibartogenic acid; -amylase; SAPONINS;
D O I：
10.1080/14786419.2015.1057730
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Two new and one known compounds were isolated from the methanol extract of Sesamum indicum leaves. By means of spectroscopic methods, their structures were elucidated and identified to be 3-epibartogenic acid (1), kaempferol 3-O-[2-O-(trans-p-coumaroyl)-3-O--L-rhamnopyranosyl]--d-glucopyranoside (2) and epigallocatechin (3). Compound 1 and 3 strongly inhibited -amylase with the IC50 values of 146.7 and 303.9M, respectively, in comparison with acarbose (IC50 124.0M).
引用
收藏
页码：311 / 315
页数：5
相关论文
共 50 条
  • [1] Flavonoid and cardenolide glycosides and a pentacyclic triterpene from the leaves of Nerium oleander and evaluation of cytotoxicity
    Siddiqui, Bina Shaheen
    Khatoon, Nasima
    Begum, Sabira
    Farooq, Ahsana Dar
    Qamar, Kehkashan
    Bhatti, Huma Aslam
    Ali, Syed Kashif
    [J]. PHYTOCHEMISTRY, 2012, 77 : 238 - 244
  • [2] Two New Pentacyclic Triterpene Saponins from the Leaves of Akebia trifoliata
    Xu, Qiao-Lin
    Wang, Jing
    Dong, Li-Mei
    Zhang, Qiang
    Luo, Bi
    Jia, Yong-Xia
    Wang, Hong-Feng
    Tan, Jian-Wen
    [J]. MOLECULES, 2016, 21 (07)
  • [3] OLEANDEROL, A NEW PENTACYCLIC TRITERPENE FROM THE LEAVES OF NERIUM-OLEANDER
    SIDDIQUI, S
    HAFEEZ, F
    BEGUM, S
    SIDDIQUI, BS
    [J]. JOURNAL OF NATURAL PRODUCTS, 1988, 51 (02): : 229 - 233
  • [4] Allelopathic Effects of Leaves of Sesamum Indicum
    Qian, Jiuli
    Li, Huashou
    [J]. 2016 2ND INTERNATIONAL CONFERENCE ON ENVIRONMENTAL POLLUTION AND PUBLIC HEALTH (EPPH 2016), 2016, 8 : 142 - 150
  • [5] New lignans from the perisperm of Sesamum indicum
    Grougnet, Raphael
    Magiatis, Prokopios
    Mitaku, Sofia
    Terzis, Aris
    Tillequin, Francois
    Skaltsounis, Alexios-Leandros
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2006, 54 (20) : 7570 - 7574
  • [6] A NOVEL PENTACYCLIC TRITERPENE ACID FROM ADENOCALYMMA-ALLIACEUM LEAVES
    MISRA, TN
    SINGH, RS
    PANDEY, HS
    PRASAD, C
    SHARMA, SC
    [J]. JOURNAL OF NATURAL PRODUCTS, 1995, 58 (07): : 1056 - 1058
  • [7] A NEW PENTACYCLIC TRITERPENE FROM ABUTILON-PAKISTANICUM
    AHMED, Z
    KAZMI, SN
    MALIK, A
    [J]. JOURNAL OF NATURAL PRODUCTS, 1990, 53 (05): : 1342 - 1344
  • [8] New pentacyclic triterpene saponins with strong anti-leishmanial activity from the leaves of Maesa balansae
    Germonprez, N
    Van Puyvelde, L
    Maes, L
    Van Tri, M
    De Kimpe, N
    [J]. TETRAHEDRON, 2004, 60 (01) : 219 - 228
  • [9] One new flavonoid from Oroxylum indicum
    Fan, Qing-Fei
    Hu, Zu-Yan
    Na, Zhi
    Tang, Hua-Shu
    Zuo, Guo-Ying
    Song, Qi-Shi
    [J]. NATURAL PRODUCT RESEARCH, 2015, 29 (19) : 1828 - 1832
  • [10] A NEW PENTACYCLIC TRITERPENE FROM ECDYSANTHERA-ROSEA
    HUANG, KF
    SY, ML
    LAI, JS
    [J]. JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 1990, 37 (02) : 187 - 189
12345