A Simulation and Techno-Economic Optimization-Based Methodology to Design Multi-Product Lignocellulosic Biorefineries

In this paper we present a novel methodology for joint optimization of process technologies, strategic capacity design and process operations. An iterative methodology is suggested to simulate and optimize nonlinear conversion processes and utilize process yields thus obtained to optimize the long term capacity design of process plants. This methodology is applied to a multiproduct biomass refinery that produces ethanol, succinic acid, and bio-electricity. Results indicate a reduction in strategic production capacity for each product due to the simulation, optimization, and utilization of nonlinear process yields.