Alcohol consumption and coronary artery calcium in middle-aged Japanese men

被引：22
|
作者：
Okamura, Tomonori [1 ]
Kadowaki, Takashi
Sekikawa, Akira
Murata, Kiyoshi
Miyamatsu, Naomi
Nakamura, Yasuyuki
El-Saed, Aiman
Kashiwagi, Atsunori
Maegawa, Hiroshi
Nishio, Yoshihiko
Takamiya, Tornoko
Kanda, Hideyuki
Mitsunami, Kenichi
Kita, Yoshikuni
Edmundowicz, Daniel
Tamaki, Shinji
Tsujita, Yasuyuki
Kuller, Lewis H.
Ueshima, Hirotsugu
机构：
[1] Shiga Univ Med Sci, Dept Hlth Sci, Shiga, Japan
[2] Shiga Univ Med Sci, Dept Radiol, Shiga, Japan
[3] Shiga Univ Med Sci, Dept Clin Nursing, Shiga, Japan
[4] Shiga Univ Med Sci, Dept Internal Med, Shiga, Japan
[5] Shiga Univ Med Sci, Med Coordinat Ctr, Shiga, Japan
[6] Univ Pittsburgh, Dept Epidemiol, Grad Sch Publ Hlth, Pittsburgh, PA 15260 USA
[7] Kyoto Womens Univ, Fac Home Econ, Dept Cardiovasc Epidemiol, Kyoto, Japan
[8] Fukushima Med Univ, Dept Hyg & Prevent Med, Fukushima, Japan
[9] Univ Pittsburgh, Med Ctr, Cardiovasc Inst, Pittsburgh, PA 15260 USA
[10] Kohka Publ Hosp, Dept Med, Shiga, Japan
来源：
AMERICAN JOURNAL OF CARDIOLOGY | 2006年 / 98卷 / 02期
关键词：
D O I：
10.1016/j.amjcard.2006.01.095
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Epidemiologic studies have investigated the relation between alcohol intake and coronary calcification, with controversial results. Furthermore, the influence of heavy drinking has not been well elucidated. In the present study, a random sample of community-based Japanese men aged 40 to 49 years without a history of cardiovascular disease (n = 245) were examined for coronary artery calcium (CAQ determined by electron-beam computed tomography and drinking status. There was a J-shaped association between alcohol intake and CAC. There was an increase of CAC in heavy drinkers (>= 46 g/day), and participants who were drinking >= 69 g/day showed a significant increase in CAC compared with never drinkers after adjusting for other cardiovascular risk factors. (c) 2006 Elsevier Inc. All rights reserved.
引用
收藏
页码：141 / 144
页数：4
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