Taste-potentiated odor aversion learning in rats with lesions of the insular cortex

被引：6
|
作者：
Lin, Jian-You [1 ]
Roman, Christopher [1 ]
Reilly, Steve [1 ]
机构：
[1] Univ Illinois, Dept Psychol, Chicago, IL 60607 USA
来源：
BRAIN RESEARCH | 2009年 / 1297卷
关键词：
Taste-potentiated odor aversion; Within-compound association; Insular cortex; Rat; FLAVOR-ILLNESS AVERSIONS; GUSTATORY NEOCORTEX; LATENT INHIBITION; COMPOUND; PROJECTIONS; EXTINCTION; NUCLEUS; PREEXPOSURE; THALAMUS; CONTEXT;
D O I：
10.1016/j.brainres.2009.08.051
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The current study assessed the influence of excitotoxic lesions of the insular cortex (IC) on taste-potentiated odor aversion (TPOA) learning. Water-deprived rats initially received a single odor-toxicosis or odor/taste-toxicosis pairing and were subsequently tested, in separate trials, with the odor and the taste stimulus. Indicating TPOA, neurologically intact rats conditioned with the odor/taste compound stimulus acquired significantly stronger odor aversions than normal rats conditioned with the odor stimulus. IC lesions disrupted TPOA, conditioned taste aversion and taste neophobia. The finding that taste did not potentiate odor aversion learning in the IC-lesioned rats provides support for the "within-compound association" analysis but is inconsistent with the "sensory-and-gate" account of TPOA learning. (c) 2009 Elsevier B.V. All rights reserved.
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页码：135 / 142
页数：8
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