Real-time in vivo imaging of adult Zebrafish brain using optical coherence tomography

被引:36
|
作者
Rao, K. Divakar [1 ]
Alex, Aneesh [1 ]
Verma, Yogesh [1 ]
Thampi, Sreeja [1 ]
Gupta, Pradeep K. [1 ]
机构
[1] Raja Ramanna Ctr Adv Technol, Laser Biomed Applicat & Instrumentat Div, Indore 452013, India
关键词
Optical coherence tomography; Zebrafish; 3-D imaging;
D O I
10.1002/jbio.200910032
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We report noninvasive imaging of the brain of adult Zebrafish (Danio rerio) using real time optical coherence tomography (OCT) capable of acquiring cross sectional 2D OCT images @ 8 frames/sec. Anatomic features such as telencephalon, tectum opticum, eminentia Granularis and cerebellum were clearly resolved in the OCT images. A 3D model of Zebrafish brain was reconstructed, for the first time to our knowledge, using these 2D OCT images. (C) 2009 by WILEYNCH Verlag GmbH & Co. KGaA. Weinheim
引用
收藏
页码:288 / 291
页数:4
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