Re-irradiation in lung disease by SBRT: a retrospective, single institutional study

被引：11
|
作者：
Caivano, Donatella [1 ]
Valenani, Maurizio [2 ]
De Matteis, Sara [2 ]
Bonome, Paolo [2 ]
Russo, Ivana [3 ]
De Sanctis, Vitaliana [2 ]
Minniti, Giuseppe [4 ]
Osti, Mattia Falchetto [2 ]
机构：
[1] CNAO Natl Ctr Oncol Hadrontherapy, Dept Radiat Oncol, Str Campeggi 53, I-27100 Pavia, Italy
[2] Univ Rome Sapienza, St Andrea Hosp, Fac Med & Psicol, Dept Radiat Oncol, Via Grottarossa 1035-1039, I-00189 Rome, Italy
[3] UPMC San Pietro FBF, Ctr Radioterapia Alta Specializzaz, Via Cassia 600, I-00189 Rome, Italy
[4] Neuromed Mediterranean Neurol Inst, Via Atinense 18, I-86077 Pozzilli, IS, Italy
来源：
RADIATION ONCOLOGY | 2018年 / 13卷
关键词：
Re-irradiation; SBRT; Lung; Primary or metastatic disease; STEREOTACTIC ABLATIVE RADIOTHERAPY; RADIATION-THERAPY; CANCER; TUMORS;
D O I：
10.1186/s13014-018-1041-y
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Background: The loco regional relapse is frequent in the lung disease. The aim of this study was to evaluate the outcomes of re-irradiation by SBRT in terms of Local Control (LC) and toxicities. Methods: From April 2011 to December 2016, twenty-two patients received a re-irradiation by SBRT. Twenty-seven lesions were treated. The medium BED(10) of re-irradiation was 100.6 Gy (range: 48-151.2 Gy) and the medium EQD2 (10) was 93.8 Gy (range: 40-126 Gy). In the previous treatment the medium BED(10) was 97.2 Gy (range: 40-120 Gy), the medium EQD2(10) was 81 Gy (range: 32.5-100 Gy). The median time between the first and the second treatment was 18 months. Results: Local Control was reached in 18 out of 27 (66%) re-irradiated lesions, with rates of 67 and 54% at 1-year and 2-years respectively. The treatment was well tolerated; the maximum recorded toxicity was Grade 3. Conclusions: Re-irradiation by SBRT may represent an option for the treatment of lung disease with good results in terms of LC and toxicity.
引用
收藏
页数：8
相关论文
共 50 条
  • [1] Re-irradiation in lung disease by SBRT: a retrospective, single institutional study
    Donatella Caivano
    Maurizio Valeriani
    Sara De Matteis
    Paolo Bonome
    Ivana Russo
    Vitaliana De Sanctis
    Giuseppe Minniti
    Mattia Falchetto Osti
    Radiation Oncology, 13
  • [2] Re-Irradiation in Lung Disease
    Caivano, D.
    De Matteis, S.
    Bonome, P.
    Russo, I.
    De Sanctis, V.
    Valeriani, M.
    Osti, M. F.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2017, 99 (02): : E443 - E444
  • [3] Lung re-irradiation with stereotactic body radiation therapy (SBRT)
    Bonome, P.
    Scaringi, C.
    Valeriani, M.
    De Sanctis, V.
    Minniti, G.
    Osti, M. F.
    RADIOTHERAPY AND ONCOLOGY, 2016, 119 : S590 - S590
  • [4] The role of hyperfractionated re-irradiation in metastatic brain disease - A single institutional trial
    AbdelWahab, MMR
    Wolfson, AH
    Raub, W
    Landy, H
    Feun, L
    Sridhar, K
    Brandon, AH
    Mahood, S
    Markoe, AM
    AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 1997, 20 (02): : 158 - 160
  • [5] Re-Irradiation for Locally Recurrent Lung Cancer: A Single Center Retrospective Analysis
    Grambozov, Brane
    Nussdorfer, Evelyn
    Kaiser, Julia
    Gerum, Sabine
    Fastner, Gerd
    Stana, Markus
    Gaisberger, Christoph
    Wass, Romana
    Studnicka, Michael
    Sedlmayer, Felix
    Zehentmayr, Franz
    CURRENT ONCOLOGY, 2021, 28 (03) : 1835 - 1846
  • [6] Evaluation of Radical Thoracic Re-Irradiation: A Single Institution Retrospective Study
    Geary, R. L.
    O'Sullivan, S.
    McDermott, S.
    Dunne, M.
    Keenan, L. G.
    Sharma, P.
    Thirion, P.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2022, 114 (03): : E362 - E363
  • [7] An institutional retrospective study in quest for apt re-irradiation dose in recurrent brain gliomas
    Chowdhary, R.
    Chufal, K.
    Pahuja, A. K.
    Ahmad, I.
    Singh, R.
    Sundari, A. V.
    Vishwakarma, G.
    RADIOTHERAPY AND ONCOLOGY, 2019, 141 : S58 - S59
  • [8] SINGLE INSTITUTIONAL RETROSPECTIVE REVIEW OF RE-IRRADIATION IN HIGH GRADE GLIOMAS IN A TERTIARY UK CENTRE
    Manik, V
    Brazil, L.
    Swampillai, A.
    Chia, K.
    Al-Salihi, O.
    NEURO-ONCOLOGY, 2022, 24
  • [9] Preliminary mono-institutional report of prostate/prostate bed SBRT re-irradiation
    Cuccia, F.
    Nicosia, L.
    Mazzola, R.
    Figlia, V.
    Giaj-Levra, N.
    Ricchetti, F.
    Rigo, M.
    Vitale, C.
    Attina, G.
    Pastorello, E.
    Corradini, S.
    Ruggieri, R.
    Alongi, F.
    RADIOTHERAPY AND ONCOLOGY, 2021, 161 : S1127 - S1127
  • [10] Re-irradiation for recurrent cervical cancer: A single institutional experience
    Li, Junyun
    Huang, Lin
    Wu, Haiying
    Li, Jia
    Cao, Xinping
    Liu, Zhimin
    CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY, 2023, 43
12345